Results 71 to 80 of about 94,471 (252)

Protective immunity against Trypanosoma cruzi [PDF]

open access: yes, 2009
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel   +2 more
core   +1 more source

Effectiveness of Organized Strategies to Enhance Access to Preventive Oral Cancer Screening Among High‐Risk Individuals in Brazil: A Randomized Clinical Trial in Primary Care

open access: yesInternational Journal of Cancer, EarlyView.
This randomized clinical trial evaluated the performance of organized risk‐based strategies to expand access to cancer preventive oral examination among vulnerable populations within the public health system of Rio de Janeiro, Brazil. Compared with an opportunistic approach, the organized invitation‐based oral cancer screening approaches systematically
Marcia Frias Pinto Marinho   +8 more
wiley   +1 more source

Economic costs of Chagas disease in Colombia in 2017: A social perspective

open access: yesInternational Journal of Infectious Diseases, 2020
Objective: To quantify the costs of Chagas disease in Colombia from a societal perspective in 2017. Methods: A cost-of-illness analysis was carried out using a prevalence-based approach.
Mario J. Olivera, Giancarlo Buitrago
doaj   +1 more source

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]

open access: yes, 2015
Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T.   +7 more
core   +2 more sources

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione   +2 more
wiley   +1 more source

Multiple causes of death related to Chagas' disease in Brazil, 1999 to 2007

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2012
INTRODUCTION: Chagas' disease is a major public health problem in Brazil and needs extensive and reliable information to support consistent prevention and control actions.
Francisco Rogerlândio Martins-Melo   +3 more
doaj   +1 more source

Feeding and defecation behavior of Triatoma rubida (Uhler, 1894) (Hemiptera: Reduviidae) under laboratory conditions, and its potential role as a vector of chagas disease in Arizona, USA [PDF]

open access: yes, 2011
Chagas disease is caused by the parasite Trypanosoma cruzi, which is transmitted to humans by blood-sucking triatomine insects. This disease is endemic throughout Mexico and Central and South America, but only a few autochthonous cases have been reported
Gregory, Teresa   +3 more
core   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos   +10 more
wiley   +1 more source

The history of Chagas disease [PDF]

open access: yesParasites & Vectors, 2014
The ancestor of Trypanosome cruzi was probably introduced to South American via bats approximately 7-10 million years ago. When the first humans arrived in the New World, a sylvatic cycle of Chagas disease was then already well established. Paleoparasitological data suggests that human American trypanosomiasis originated in the Andean area when people ...
openaire   +5 more sources

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos   +8 more
wiley   +1 more source

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