Results 61 to 70 of about 92,352 (267)

Protective immunity against Trypanosoma cruzi [PDF]

, 2009
Upon infection, Trypanosoma cruzi triggers a strong immune response that has both protective and pathological consequences. In this work, several important questions regarding protective immunity are reviewed.
Basombrío, Miguel Ángel Manuel, Padilla, Ángel Marcelo, Parodi Ramoneda, Cecilia María   +2 more
core   +1 more source

Synthesis and In Vitro Activity of Hypofuran B and Analogs Against Plasmodium Falciparum and Trypanosoma Cruzi

ChemMedChem, EarlyView.
Hypofuran B, drynaran, and a series of analogs are obtined by crossed aldol condensation from furfural dereivatives. Compunds are tested for in vitro activity agaisnt Trypanosoma cruzi and Plasmodium falciparum. Best results are obtained Against P. falciparum, with IC50 values ranging from 5,35 to 10,35 µg mL−1.
Cristiane Aparecida Franco, Jodieh Oliveira Santana Varejão, Isabela Penna Ceravolo, Victória Miranda Machado, Antoniana Ursine Krettli, Daniela de Melo Resende, Silvane Maria Fonseca Murta, Felipe Terra Martins, Eduardo Jorge Pilau, Vinícius Ribeiro Montes, Markus Kohlhoff, Eduardo V. V. Varejão   +11 more
wiley   +1 more source

The chronic gastrointestinal manifestations of Chagas disease

Clinics, 2009
Chagas disease is an infectious disease caused by the protozoan Trypanosoma cruzi. The disease mainly affects the nervous system, digestive system and heart.
Nilce Mitiko Matsuda, Steven M. Miller, Paulo R. Barbosa Evora   +2 more
doaj   +1 more source

Patterns of Cervical Metastases and Implications for Neck Management in Minor Salivary Gland Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Objectives Minor salivary gland cancer (MiSGC) is a rare and heterogeneous disease, with different degrees of tumor aggressiveness. The scarce data in the literature show that the presence of lymph node metastases (LNMs) negatively impacts the prognosis.
Eduardo Wanderley Estanislau da Costa, Pedro Nicolau‐Neto, Paula Moretz‐Sohn, Bernardo Cacciari Peryassu, Emilson de Queiroz Freitas, Luis Felipe Ribeiro Pinto, Fernando Luiz Dias   +6 more
wiley   +1 more source

Chagas disease: a report of 17 suspected cases in Japan, 2012–2017

Tropical Medicine and Health, 2019
Background There are no reports on the prevalence of Chagas disease in Japan. Furthermore, screening programs and access to diagnosis and treatment have not been established.
Kazuo Imai, Kazuhisa Misawa, Morichika Osa, Norihito Tarumoto, Jun Sakai, Kei Mikita, Yusuke Sayama, Yuji Fujikura, Akihiko Kawana, Takashi Murakami, Shigefumi Maesaki, Sachio Miura, Takuya Maeda   +12 more
doaj   +1 more source

Cardiovascular risk profile according to World Health Organization medical eligibility criteria for contraceptive use of women using hormonal contraception in Rio de Janeiro state, Brazil

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Hormonal contraception, especially combined oral contraceptives, is associated with an increase in cardiovascular risk. Thus, we aimed to analyze the use of hormonal contraceptive methods in the state of Rio de Janeiro (Brazil), with a focus on determining whether contraceptive use follows the cardiovascular profile of women ...
Isabela Pereira Fonseca Brusth, Juliana Montani Raimundo, Helene Nara Henriques Blanc   +2 more
wiley   +1 more source

Comparative analysis of health-related fitness in patients with acute versus chronic Chagas disease

Biomédica: revista del Instituto Nacional de Salud
Introduction. Although Chagas disease causes high levels of morbidity, the muscle function and tolerance to physical activity in Chagas disease patients are still not completely understood. Objective.
Clara Narcisa Silva Almeida, Ariane Cardoso Vasconcelos, Caroline da Silva Sousa, Nivea Thayanne Melo Silva, Dilma do Socorro Moraes de Souza, Carlos Alberto Marques de Carvalho, Suellen Alessandra Soares de Moraes, Laura Maria Tomazi Neves   +7 more
doaj   +1 more source

Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]

, 2019
The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core   +1 more source

Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]

, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad, Miranda, Mariana Reneé, Pereira, Claudio Alejandro, Reigada, Chantal, Valera Vera, Edward Augusto   +4 more
core   +1 more source

Chagas disease 101 [PDF]

Nature, 2010
It is 101 years since Carlos Chagas discovered the parasite responsible for the disease that now bears his name. What progress has been made since this discovery? Here Julie Clayton gives the low-down on Chagas disease.
openaire   +2 more sources