Results 81 to 90 of about 92,352 (267)

Chagas disease and systemic autoimmune diseases among Bolivian patients in Switzerland

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Chronic cardiomyopathy occurs in 20-40% of the patients with Chagas disease. Autoimmune mechanisms may contribute to its pathogenesis. We diagnosed several cases of systemic autoimmune diseases among Bolivian migrants in Geneva with a high ...
Yves Jackson, Drenusha Vieira de Mello Pula, Axel Finckh, Carlo Chizzolini, François Chappuis   +4 more
doaj   +1 more source

Chemotherapy of Chagas' disease: state of the art and perspectives for the development of new drugs [PDF]

, 2009
Neglected diseases are a major global cause of illness, long-term disability and death. Chagas' disease is a parasitic infection widely distributed throughout Latin America, with devastating consequences in terms of human morbidity and mortality.
ANDRICOPULO, Adriano Defini, DESSOY, Marco A., DIAS, Luiz C., OLIVA, Glaucius, SILVA, Jean Jerley N., THIEMANN, Otavio Henrique   +5 more
core   +2 more sources

Pupillometry in Chagas disease

Arquivos Brasileiros de Oftalmologia, 2018
We investigated parasympathetic innervation abnormalities of the iris sphincter and ciliary muscles in chronic Chagas disease by measuring pupillary diameter and intraocular pressure.A group of 80 patients with Chagas disease was compared with 76 healthy individuals without chagasic infection.
Vargas, Diva, Castro, Cleudson
openaire   +4 more sources

Ruthenium‐Catalyzed CH Alkenylation of Trypanocidal Naphthoquinones: A Mechanistic Benchmarking Study

ChemistryOpen, EarlyView.
Computational roadmap to click‐ready quinones. Quantum chemical analysis reveals how substituents modulate the reactivity of trypanocidal naphthoquinones in Ru‐catalyzed CH alkenylation, guiding the design of sulfonyl‐fluoride scaffolds for next‐generation antiparasitic agents.
Esther R. S. Paz, Cauê P. Souza, Joyce C. De Oliveira, Renata G. Almeida, Chonny Herrera‐Acevedo, Sulaiman Lakoh, Guilherme A. M. Jardim, Eufrânio N. da Silva Júnior, Felipe Fantuzzi   +8 more
wiley   +1 more source

Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]

, 2018
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo, A Montalvetti, A Rassi, AB Penissi, AE Eakin, AH Kolien, AJ Solari, AM Sánchez, Ana Yecê das Neves Pinto, C Brack, CF Silva Da, D Gonzalez-Pacanowska, DA Campbell, DA Johnston, DJ Hammond, DV Andrade, E Bontempi, E Lozano, E Lozano, E Lozano, EO Ogbadoiyi, ES Garcia, ES Lozano, F Dos Reis, FR Opperdoes, FR Opperdoes, FR Opperdoes, FS Laranja, H Meyer, H Meyer, J Aldunate, J Lukes, J McKerrow, J Mottram, JA Urbina, JA Urbina, JA Urbina, JA Urbina, JC Engel, JC Linder, JCP Dias, JCP Dias, JD Bergstrom, JD Maya, JF Turrens, JJ Marr, JL Avila, JL Avila, Juliano de Toledo, K Lazardi, K Miranda, K Miranda, KH Lee, L Simpson, LV Muschietti, M Meirelles, M Nieto, MC Elias, MCQB Elias, MR Ariyanayagam, MR Ariyanayagam, NM Sayed El, O Campetella, OS Giordano, OS Giordano, P Barrera, P Webster, PF Pimenta, R Docampo, S Sepúlveda-Boza, SD Brengio, SR Wilkinson, T Souto-Padron, T Souto-Padron, T Souto-Padron, T Souto-Padron, TA Shapiro, TS Tiuman, V Jimenez-Ortiz, V Sülsen, VP Sülsen, VP Sülsen, VV Costantino, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, Wanderley de Souza, WE Gutteridge   +90 more
core   +1 more source

Understanding preferences for nature's contributions to people between and within social actors sheds insights for inclusive conservation

People and Nature, EarlyView.
Abstract Despite calls for wider inclusion of diverse actors in conservation management, researchers tend to lump actors together into one group, potentially overlooking heterogeneity within the groups themselves—in turn, hampering inclusiveness. The risk of stereotyping social actors and oversimplifying their differentiated preferences for Nature's ...
Milena Gross, Tuyeni Heita Mwampamba, John Sanya, Jasmine Pearson, Jennifer Sesabo, Berta Martín‐López   +5 more
wiley   +1 more source

Mapping of Chagas disease research: analysis of publications in the period between 1940 and 2009

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: Publications are often used as a measure of success in research work. Chagas disease occurs in Central and Southern America. However, during the past years, the disease has been occurring outside Latin America due to migration from endemic ...
José Manuel Ramos, Gregorio González-Alcaide, Joaquín Gascón, Félix Gutiérrez   +3 more
doaj   +1 more source

Discussing the Score of Cardioembolic Ischemic Stroke in Chagas Disease

Tropical Medicine and Infectious Disease, 2020
Chagas disease is an important infection in Latin America but it is also reported in non-endemic countries all over the world. Around 30% of infected patients develop chronic Chagas cardiopathy, which is responsible for most poor outcomes, mainly heart ...
Fernanda de Souza Nogueira Sardinha Mendes, Mauro Felippe Felix Mediano, Rudson Santos Silva, Sergio Salles Xavier, Pedro Emmanuel Alvarenga Americano do Brasil, Roberto Magalhães Saraiva, Alejandro Marcel Hasslocher-Moreno, Andrea Silvestre de Sousa   +7 more
doaj   +1 more source

Identifying Current and Missing Knowledge in the Control of Pyrethroid-Resistant Triatoma Infestans, Vector of Chagas Disease [PDF]

, 2017
Triatomines are blood-sucking bugs that occur mainly in Latin America. They are vectors of Trypanosoma cruzi, the parasite that causes Chagas disease.
Picollo, Maria Ines, Roca Acevedo, Gonzalo   +1 more
core   +1 more source

Challenges and Opportunities in State‐of‐the‐Art Proteomics Analysis for Biomarker Development From Plasma Extracellular Vesicles

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound particles secreted by cells, playing crucial roles in intercellular communication. The composition of EVs can undergo changes in response to stress and disease conditions, making them excellent biomarker candidates.
Panshak P. Dakup, Ivo Diaz Ludovico, Youngki You, Chaitra Rao, Javier Flores, Lisa M. Bramer, Marian Rewers, Bobbie‐Jo M. Webb‐Robertson, Thomas O. Metz, Raghavendra G. Mirmira, Emily K. Sims, Ernesto S. Nakayasu   +11 more
wiley   +1 more source