Results 101 to 110 of about 307,494 (239)

4,8,9,10-Tetrakis(4-fluorophenyl)-1,3-diazatricyclo[3.3.1.1]decan-6-one

Acta Crystallographica Section E, 2009
In the title compound, C32H24F4N2O, all four six-membered rings that constitute the diazaadamantanone cage adopt chair conformations. Two of the four fluorophenyl substituents occupy axial positions and the other two occupy equatorial positions relative ...
S. Natarajan, V. Sudha Priya, V. Vijayakumar, J. Suresh, P. L. Nilantha Lakshman   +4 more
doaj   +1 more source

Observation of interacting Josephson vortex chains by magnetic force microscopy

Physical Review Research, 2020
The ability to control Josephson vortices is instrumental for development of superconducting cryoelectronics. However, direct visualization of multivortex states in Josephson junctions is a challenging task.
Sergey Yu. Grebenchuk, Razmik A. Hovhannisyan, Viacheslav V. Dremov, Andrey G. Shishkin, Vladimir I. Chichkov, Alexander A. Golubov, Dimitri Roditchev, Vladimir M. Krasnov, Vasily S. Stolyarov   +8 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

MDS and MHDR Cyclic Codes over Finite Chain Rings

Journal of Mathematics
This work establishes a unique set of generators for a cyclic code over a finite chain ring. Towards this, we first determine the minimal spanning set and rank of the code.
Monika Dalal, Sucheta Dutt, Ranjeet Sehmi   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Crystal structure of 4,6-bis[(E)-4-bromostyryl]-2-(butylsulfanyl)pyrimidine

Acta Crystallographica Section E, 2014
In the title compound, C24H22Br2N2S, the dihedral angles between the central pyrimidine ring and the pendant bromobenzene rings are 11.02 (11) and 13.20 (12)°. The butyl side chain adopts a gauche conformation [C—C—C—C = −67.4 (4)°]. In the crystal, weak
Wang Yu, Jingbao Song, Aijian Wang
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Rings with divisibility on ascending chains of ideals

International Electronic Journal of Algebra
According to Dastanpour and Ghorbani, a ring $R$ is said to satisfy divisibility on ascending chains of right ideals ($A C C_{d}$) if, for every ascending chain of right ideals $I_{1} \subseteq I_{2} \subseteq I_{3} \subseteq I_{4} \subseteq \ldots $ of $R$, there exists an integer $k \in \mathbb{N}$ such that for each $i \geq k$, there exists an ...
SAFI, Oussama Aymane Es, MAHDOU, Najib, YOUSIF, Mohamed   +2 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source