Results 81 to 90 of about 307,494 (239)

2-{[4-(Dimethylamino)benzylidene]amino}phenyl disulfide

open access: yesActa Crystallographica Section E, 2011
In the title molecule, C30H30N4S2, the two benzene rings connected through the disulfide chain form a dihedral angle of 88.7 (1)°, and the two benzene rings in the benzylideneaniline fragments form dihedral angles of 34.0 (1)
Qing-Peng He, Li Dai, Bo Tan
doaj   +1 more source

A study of the morphology, dynamics, and folding pathways of ring polymers with supramolecular topological constraints using molecular simulation and nonlinear manifold learning

open access: yes, 2017
Ring polymers are prevalent in natural and engineered systems, including circular bacterial DNA, crown ethers for cation chelation, and mechanical nanoswitches.
Ferguson, Andrew, Wang, Jiang
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Quantum Transport in Molecular Rings and Chains

open access: yes, 1999
We study charge transport driven by deformations in molecular rings and chains. Level crossings and the associated Longuet-Higgins phase play a central role in this theory.
Dubrovin B. A.   +7 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

4,4′-(o-Phenylenedioxydimethylene)dipyridinium dinitrate

open access: yesActa Crystallographica Section E, 2009
The cation of the salt, C18H18N2O22+·2NO3−, lies about a twofold rotation axis. The pyridinium ring is almost coplanar with the phenylene ring [dihedral angle between rings = 5.69 (9)°].
Ping Zou   +4 more
doaj   +1 more source

Weak dimension of FP-injective modules over chain rings

open access: yes, 2015
It is proven that the weak dimension of each FP-injective module over a chain ring which is either Archimedean or not semicoherent is less or equal to ...
Couchot, Francois
core   +3 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

(E)-N-[2-(Biphenyl-4-ylvinyl)phenyl]furan-2-carboxamide

open access: yesActa Crystallographica Section E, 2008
In the title molecule, C25H19NO2, the furyl ring is twisted by 46.3 (1)° with respect to the phenylene ring bearing the amido group. In the stilbene unit, the two phenylene rings (i.e.
Noel F. Thomas   +4 more
doaj   +1 more source

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