Results 121 to 130 of about 5,972,156 (311)

Structures and Technologies for Stepwise Implementation of Adaptive Supply Chain [PDF]

open access: yes, 2005
Falling margins, globalization, and accelerating innovation cycles are forcing businesses to switch from traditional (linear and sequential) supply chains to adaptive supply chain that possess the flexibility needed to respond to the environment in real ...
Davidrajuh, Reggie   +1 more
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

A quantitative relationship between Tgs and chain segment structures of polystyrenes

open access: yesPolímeros
The glass transition temperature (Tg) is a fundamental characteristic of an amorphous polymer. A quantitative structure-property relationship (QSPR) based on error back-propagation artificial neural network (ANN) was constructed to predict Tgs of 107 ...
Xinliang Yu, Xianwei Huang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Shrimp Industry of Bangladesh: A Supply Chain Issue [PDF]

open access: yes, 2020
Purpose: The purpose of this study is to evaluate the shrimp industry of Bangladesh in terms of Porter’s 5-forces model. It also aims to trace the supply chain of the shrimp industry. Methods: The study uses both primary and secondary data.
Jahangir, Rizwana
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Improving supply chain planning with advanced analytics : analyzing lead time as a case study

open access: yes, 2018
Thesis: M. Eng. in Supply Chain Management, Massachusetts Institute of Technology, Supply Chain Management Program, 2018.Cataloged from PDF version of thesis.Includes bibliographical references (pages 72-74).Over the years, supply chain management has ...
Yau, Darryl (Chun Him)
core  

Chain governance structures: the European traditional food sector

open access: yes, 2009
Purpose - The purpose of the paper is to identify chain-level, product-, and country-specific characteristics, of chain governance structures in the traditional food sector in the European Union (EU).
Gellynck, Xavier   +3 more
core   +1 more source

Tax implications of transfer pricing on supply chain management [PDF]

open access: yes, 2011
Includes bibliographical references (leaves 114-120).Increased globalisation has lead to centralised risk management and decision-making in multinational enterprises, which gives rise to the principle of tax efficient supply chain management and the need
Eich, Bettina
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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