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Polymorphism and conformerism in chalcones
CrystEngComm, 2016Herein two solid state phenomena have been observed in two chalcones. Firstly, polymorphism has been found in (E)-1-(2-aminophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one (1). This compound crystallizes with only one conformer rather than three in the known reported structure. In the polymorphs, the conformation of the phenyl ring bonded to carbonyl
Felipe T. Martins +3 more
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An updated patent review of therapeutic applications of chalcone derivatives (2014-present)
Expert Opinion on Therapeutic Patents, 2019Introduction: Chalcone or benzylideneacetophenone or 1,3-diphenyl-2-propene-1-one is a natural product comprising of two aromatic rings connected together by a three-carbon α, β unsaturated carbonyl bridge.
Debarshi Kar Mahapatra +2 more
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Molecular Crystals and Liquid Crystals, 2002
The photoisomerization behavior of benzylidene-acetophenones known as chalcones, was studied. We synthesized the chalcone derivatives that have ether groups at 4 and 4′ positions. Due to the electron donating ability of the ether oxygen, the bond order of the single bond between two phenyl ring of the chalcone strengthened, which eventually increased ...
Kyung-Hoon Jung +2 more
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The photoisomerization behavior of benzylidene-acetophenones known as chalcones, was studied. We synthesized the chalcone derivatives that have ether groups at 4 and 4′ positions. Due to the electron donating ability of the ether oxygen, the bond order of the single bond between two phenyl ring of the chalcone strengthened, which eventually increased ...
Kyung-Hoon Jung +2 more
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Inhibiting Firefly Bioluminescence by Chalcones
Analytical Chemistry, 2017Chalcone refers to an aromatic ketone and an enone that constitutes the central core for various important biological compounds in drug discovery. Moreover, the firefly luciferase (Fluc) as the bioluminescent reporter has been widely used in life science research and high-throughput screening (HTS).
Huateng Zhang +8 more
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Recent Synthetic Methodologies for Chalcone Synthesis (2013-2018)
Current Organocatalysis, 2019An up-to-date short review of the chalcone methodologies is presented, which is the most interesting and beneficial for choosing the desired protocol to synthesize suitable derivatives of chalcones.
Saba Farooq and Zainab Ngaini
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Structural study on chalcone derivatives
Synthetic Metals, 1994Abstract Crystal structures of several SHG-active chalcone derivatives were determined by X-ray analysis. The phase-matching direction of a 1-(3-thienyl)-3-(4-chlorophenyl)-2-propen-1-one crystal is discussed by relating to its molecular packing in the crystal.
K. Kozawa +3 more
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Chalcone synthesis, properties and medicinal applications: a review
Environmental Chemistry Letters, 2020Aluru Rammohan +4 more
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Toxicological assessment of Ashitaba Chalcone
Food and Chemical Toxicology, 2015The plant Angelica keiskei contains two main physiologically active flavonoid chalcones, 4-hydroxyderricin and xanthoangelol. Known as ashitaba in Japan, powder from the sap is widely consumed for its medicinal properties in Asia as a dietary supplement. Limited previously reported mammalian studies were without evidence of toxicity.
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Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review.
European journal of medicinal chemistry, 2020Hua-Li Qin +4 more
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Chalcones, Aurones and Dihydrochalcones
1975This chapter will treat three small groups of flavonoids: chalcones, dihydrochalcones and aurones. In the case of chalcones and aurones, placing them together in the same chapter reflects their traditional treatment as ‘anthochlor’ pigments. This term was originally coined to identify a group of yellow pigments which turned red in the presence of ...
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