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ChemInform Abstract: Bioactivities of Chalcones
ChemInform, 1999AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Michael A. Beazely +3 more
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Acta Crystallographica Section C Crystal Structure Communications, 1993
1-(7-Hydroxy-2,2-dimethylchroman-6-yl)-3-phenyl-2-propen-1-one, C 20 H 20 O 3 , M r =308.38, P2 1 /a, a=12.002 (2), b=11.013 (2), c=12.652 (3) A, β=106.24 (3) o , V=1605.6 A 3 , Z=4, D m =1.26 (2), D x =1.275 Mg m -3 , λ(Mo Kα)=0.71069 A, μ=0.079 mm -1 , F(000)=656, T=293 K, R=0.037, wR=0.034 for 892 reflections with I>3σ(I).
ALEX, G +5 more
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1-(7-Hydroxy-2,2-dimethylchroman-6-yl)-3-phenyl-2-propen-1-one, C 20 H 20 O 3 , M r =308.38, P2 1 /a, a=12.002 (2), b=11.013 (2), c=12.652 (3) A, β=106.24 (3) o , V=1605.6 A 3 , Z=4, D m =1.26 (2), D x =1.275 Mg m -3 , λ(Mo Kα)=0.71069 A, μ=0.079 mm -1 , F(000)=656, T=293 K, R=0.037, wR=0.034 for 892 reflections with I>3σ(I).
ALEX, G +5 more
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Stereoselectivity of chalcone isomerase with chalcone derivatives: a computational study
Journal of Molecular Modeling, 2013Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcones into flavonoids. The activity of CHI is essential for the biosynthesis of flavonoids precursors of floral pigments and phenylpropanoid plant defense compounds. In the present study, we explored the detailed binding structures and binding free energies for two different ...
Yuan Yao +3 more
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Anticancer activities of novel chalcone and bis-chalcone derivatives
Bioorganic & Medicinal Chemistry, 2006A series of novel chalcones and bis-chalcones containing boronic acid moieties has been synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB-231 (estrogen receptor-negative) and MCF7 (estrogen receptor-positive) cell lines and against two normal breast epithelial cell lines, MCF-10A and MCF-12A.
Peng Huang +5 more
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Chemistry of Heterocyclic Compounds, 1971
Previously undescribed aromatic α-keto oxides have been obtained by the epoxidation of chalcones with alkaline hydrogen peroxide in methanolic solution.
V. F. Belyaev, N. M. Yatsevich
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Previously undescribed aromatic α-keto oxides have been obtained by the epoxidation of chalcones with alkaline hydrogen peroxide in methanolic solution.
V. F. Belyaev, N. M. Yatsevich
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Mini-Reviews in Medicinal Chemistry, 2021
Quinazoline and/or chalcones derivatives are important targets in several areas of chemical sciences, mainly, in the medicinal chemistry and pharmaceutical research. The purpose of this review was to systematize the information available in the literature, including patents, regarding the benefits, exerted by the combination of these two ...
Dennis Russowsky +2 more
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Quinazoline and/or chalcones derivatives are important targets in several areas of chemical sciences, mainly, in the medicinal chemistry and pharmaceutical research. The purpose of this review was to systematize the information available in the literature, including patents, regarding the benefits, exerted by the combination of these two ...
Dennis Russowsky +2 more
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Anti‐tumorigenic chalcones [PDF]
STEM CELLS, 1994 On the basis of our recent findings that licochalcone A isolated from Xin-jiang licorice showed anti-inflammatory and anti-tumorigenic activities, we synthesized more than 40 chalcone derivatives to examine their anti-tumorigenic activities. In vitro inhibitory activity against phosphorylation of phospholipids promoted by tetradecanoylphorbol-13 ...
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Chalcones and Bis-Chalcones Analogs as DPPH and ABTS Radical Scavengers
Letters in Drug Design & Discovery, 2021Background:A number of synthetic scaffolds, along with natural products, have been identified as potent antioxidants. The present study deals with the evaluation of varyingly substituted, medicinally distinct class of compounds “chalcones and bis-chalcones” for their antioxidant potential.Methods:In vitro radical scavenging activities were performed on
Adebayo Tajudeen Bale +9 more
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Chemical sensing of chalcones by voltammetry: trans-Chalcone, cardamonin and xanthohumol
Electrochimica Acta, 2013Abstract Xanthohumol (XN) and cardamonin (CD) belong to the chemical class of chalcones which are phenolic compounds of large interest due to their health promoting properties. In the present work, their electrochemical behavior on a hanging mercury drop electrode (HMDE) is compared to trans -chalcone by means of cyclic voltammetry (CV).
Tavares, E.M. +8 more
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Polarographic reduction of chalcones [PDF]
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1972 1. The influence of substituents on the polarographic reduction of chalcones and their vinylogs is exerted chiefly according to an inductive mechanism, and as a result of this decreased rapidly with increasing length of the chain of double bonds. 2.
V. F. Kucherov +2 more
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