Results 231 to 240 of about 3,527,028 (317)

Buprenorphine extended-release (Ethiqa XR) impacts the immunological response in mice exposed to aerosolized <i>Burkholderia pseudomallei</i> or <i>Yersinia pestis</i>. [PDF]

Front Immunol
Rodriguez CI, Klimko CP, Davies ML, Dankmeyer JL, Rill NO, Hunter M, Smith BA, Wheeler TK, Webster-Zahnow WM, Swamotz AM, Hernandez-Viezcas Y, Xander C, Martinez EE, Toothman RG, Mlynek KD, Bozue JA, Qiu J, Biryukov SS, Cote CK.   +18 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Towards improved balance exercise recommendations for older adults: integrating balance intensity into training dosage. [PDF]

Eur Rev Aging Phys Act
Farlie M, Sibley K, Brusola G, Espy D, Jolliffe L, Lyon M, McArthur C, Okubo Y, Bouchard D, Haines T.   +9 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Dietary gallic acid supplementation alleviates LPS-induced inflammatory responses and intestinal barrier damage in chickens at an early age. [PDF]

Poult Sci
Xiong T, Chen Z, Hassan M, Huang Y, Ye J, Fan Q, Zhu C, Jiang S.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The mediating role of personality traits in the relationship between challenge threat appraisal and pro-antisocial behaviors. [PDF]

Front Psychol
Sitti S, Dincel S, Solmaz S, Emre Yarayan Y, Şimşek B.   +4 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Relieving or Aggravating? The Longitudinal Moderating Role of Challenge and Hindrance Academic Stressors on the Relationship Between Leisure-Time Physical Activity and Context-Specific Anxiety Symptoms Among University Faculty. [PDF]

Behav Sci (Basel)
Li H, Shi M, Zhu Q.
europepmc   +1 more source