Results 91 to 100 of about 13,780,988 (298)

Dissecting the Genomic Architecture of Resistance to Eimeria maxima Parasitism in the Chicken

open access: yesFrontiers in Genetics, 2018
Coccidiosis in poultry, caused by protozoan parasites of the genus Eimeria, is an intestinal disease with substantial economic impact. With the use of anticoccidial drugs under public and political pressure, and the comparatively higher cost of live ...
Kay Boulton   +20 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Challenge

open access: yes, 1991
BACKGROUND INFORMATION The Morehouse Research Institute (MRI), established in 1990, promotes an interdisciplinary program of scholarship. It is designed to generate, disseminate, and exchange information which can guide public policy and programs ...
Mukenge, Ida Rousseau
core   +1 more source

The Life Sciences Challenge: delivering an all-Wales bilingual inter-school competition for over 10 years and throughout a global pandemic

open access: yesResearch for All
The Life Sciences Challenge/Her Gwyddorau Bywyd is an all-Wales bilingual inter-school competition for Year 10 pupils, designed and delivered by students, staff scientists and engagement professionals within Cardiff University School of Medicine.
doaj   +2 more sources

Clinical and measurement variables affecting halitosis intensity following cysteine challenge test

open access: yesScientific Reports
The cysteine challenge test is a reliable and efficient method for halitosis diagnosis and assessing treatment effectiveness by measuring the capacity to produce hydrogen sulfide.
Wanki Lee   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Sequencing approaches to identify distal jejunum microbial community composition and function in broiler chickens fed anti-interleukin-10 during coccidiosis and necrotic enteritis challenge

open access: yesPoultry Science
: Strategies to counteract interleukin (IL)-10-mediated immune evasion by Eimeria spp. during coccidiosis- like anti-IL-10 antibodies- may protect broiler chicken health and reduce incidence of secondary necrotic enteritis (Clostridium perfringens) via ...
K. Fries-Craft   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A potent combination microbicide that targets SHIV-RT, HSV-2 and HPV.

open access: yesPLoS ONE, 2014
Prevalent infection with human herpes simplex 2 (HSV-2) or human papillomavirus (HPV) is associated with increased human immunodeficiency virus (HIV) acquisition.
Larisa Kizima   +21 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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