Results 111 to 120 of about 2,120,441 (365)

The African Transport Systems Database - a geospatial database of multi-modal connected networks

open access: yesScientific Data
We present the first comprehensive geolocated multi-modal transport database for the whole continent of Africa, the African Transport Systems Database (AfTS-Db), including road, rail, aviation, maritime and inland waterway networks.
Silvia Colombo   +6 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Strategy Development for a Successful Change Implementation at Barloworld

open access: yes, 2020
Businesses exist to generate profits for the shareholders, pay taxes and to pay their employees. Therefore, managers constantly look for better ways to maximise profits.
King Costa   +3 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Success factors of change management in the European steel market [PDF]

open access: yes, 2012
Information technology (IT) has become the basis for organisational processes, productivity and competitiveness. IT thus has become one of the top drivers for organisational change.
Hetkamp, Michael
core  

AI-Enabled Enterprise Management for Digital Entrepreneurship: Integrating HR Analytics, Financial Planning, and Marketing Strategy Towards Sustainable Business Performance

open access: yesJournal of Asia Entrepreneurship and Sustainability
The current accelerated development of the artificial intelligence (AI) in all the organisational functions has opened new avenues of optimising the performance of the entire enterprise. In the present paper, a single theoretical and empirical framework
Dr. Ashok Kumar   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Decision-making for climate change adaptation: A systems thinking approach [PDF]

open access: yes, 2013
The impacts of climate change are exacerbated by inefficient adaptation and mitigation decision making, due to the complexity of the decision-making environment. As a consequence, there is no single approach to planning and decision making.
Kambiz Maani, Maani, Kambiz
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

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