Results 161 to 170 of about 6,834,000 (312)

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

New Sparks and Spots: Molecular Imaging with Positron Emission Tomography Will Change Management of Cushing's Disease. [PDF]

open access: yesEndocrinol Metab (Seoul)
Reincke M   +8 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Staging CT chest for cT1a renal masses: Does it change management? [PDF]

open access: yesBJUI Compass
Ilangovan S   +9 more
europepmc   +1 more source

CHANGE MANAGEMENT OF ORGANIZATION IN THE KNOWLEDGE ECONOMY [PDF]

open access: yes
The process of change involves major crises and conflicts and is not usually predictable. Change leadership is not directed only to improve results, but also to determine people to behave in line with the perspectives, values and beliefs as "correct ...
Laurentiu Barcan Ph. D Student
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Legislation against girl circumcision: a cultural psychological understanding of prohibition

open access: yesSexual and Reproductive Health Matters, 2019
Ernst Patrick Graamans   +2 more
doaj   +1 more source

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