Results 81 to 90 of about 2,120,441 (365)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Change and learning strategies in large scale change programs

open access: yes, 2013
Purpose The study identifies the variation of change strategies used in a complex large scale change program in health and social services in Sweden, aimed at changing professionals' health promoting practices.
Elisabet Höög   +14 more
core   +1 more source

Boundary Layer Modelling of Flow Acceleration and Energy Transfer Effects in Smart Pavement Design

open access: yesScience, Engineering and Technology
The integration of remote technology into the construction industry has advanced the emergence of smart, self-learning infrastructure across all levels of land transportation design and development. However, energy harvesting capabilities for smart road
Festus Fameso   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

DEM 216: Organizational Change and Change Management

open access: yes, 2017
DEM 216: Organizational Change and Change Management Final ExamDaystar ...
School of Arts and Humanities, Department of Education
core  

Uncovering hub genes and screening of natural CDK1 inhibitors for targeting in hepatocellular carcinoma

open access: yesIn Silico Research in Biomedicine
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality, necessitating the identification of novel therapeutic targets. In this study, we utilized microarray-based genomic analysis to identify key up regulated genes in HCC ...
Yashvi Patel   +2 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

The batteries of change. Is your organisation energised for change

open access: yes, 2018
This white paper by Prof Peter De Prins, Prof Geert Letens and Prof Kurt Verweire sets out a new change model and outlines how you can use it to make lasting, effective change happen in your ...
Verweire, Kurt   +2 more
core  

Improving implementation : organisational change and project management /

open access: yes
"The business of government is necessarily diverse, changing and of considerable scale. A focus on improving the implementation of government programs and initiatives is important because the community expects the Government to deliver on its policies ...
Wanna, John,editor.
core   +1 more source

What do we transfer in case discussions? The hidden curriculum in medicine…

open access: yesPerspectives on Medical Education, 2013
Medical students and junior doctors learn according to the formal curriculum, but they also learn unwritten rules, the specific logic of the medical world, through a socialization process called ‘the hidden curriculum’. The result of the process seems to
Yolande Witman
doaj   +1 more source

Home - About - Disclaimer - Privacy