Results 61 to 70 of about 5,387,813 (292)
Anisotropic electrical resistivity of LaFeAsO: evidence for electronic nematicity [PDF]
, 2012 Single crystals of LaFeAsO were successfully grown out of KI flux. Temperature dependent electrical resistivity was measured with current flow along the basal plane, \rho_perpend(T), as well as with current flow along the crystallographic c-axis ...
Doert, Th. +5 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Applied SciencesThe aim of this study was to investigate associations and differences between dynamic strength index (DSI) and multi-directional jumping, linear and curvilinear sprinting, and change of direction (CoD).
Jernej Pleša +4 more
doaj +1 more source
Change of Direction in the Biomechanics of Atherosclerosis [PDF]
Annals of Biomedical Engineering, 2014 The non-uniform distribution of atherosclerosis within the arterial system has been attributed to pro-atherogenic influences of low, oscillatory haemodynamic wall shear stress (WSS) on endothelial cells (EC). This theory is challenged by the changes in lesion location that occur with age in human and rabbit aortas.
Mohamied, Yumnah +5 more
openaire +5 more sources
Dynamics of electron currents in nanojunctions with time-varying components and interactions
, 2017 We study the dynamics of the electron current in nanodevices where there are time-varying components and interactions. These devices are a nanojunction attached to heat baths and with dynamical electron-phonon interactions and a nanojunction with photon ...
Bayocboc, Francis A. +2 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Journal of Functional Morphology and KinesiologyBackground/Objectives: Futsal players need peak strength, functional capacity, speed, and explosive lower-limb power for optimal performance. The aim of this study was to (i) characterize and compare anthropometric characteristics, lower limb strength ...
João P. Oliveira +5 more
doaj +1 more source
Factor Supplies and the Direction of Technical Change [PDF]
In this paper, we empirically address the hypothesis that there is a relationship between the supply of human capital and the rate and direction of skill-biased technical change (SBTC).
Svaleryd, Helena, Vlachos, Jonas
core