Results 71 to 80 of about 169,052,029 (285)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Seeds of Change

open access: yes, 2008
How did the 20th century change the way Americans live? This ABC News program anchored by Peter Jennings examines daily life during the early 1900s--when William McKinley was President, a loaf of bread cost only a few cents, horsepower really meant ...

core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Our changing planet : the U.S. Climate Change Science Program for fiscal years ... : a report

open access: yes, 2003
Annual report of the U.S. Climate Change Science Program documenting activities and research, goals for the upcoming year, proposed budget considerations, and other information about the organization for fiscal year ...
Climate Change Science Program (U.S.)
core  

A change in direction [PDF]

open access: yesNature Methods, 2006
Many young scientists know the pain of unsuccessfully lobbying an advisor to back an 'impractical' experimental approach, and David Schwartz was no exception. While working on his senior research project at Harvard University in the late 1970s, he had conceived of a method for separating DNA molecules of unprecedented size by electrophoresis, using ...
openaire   +1 more source

Predicting UHMWPE wear: decreasing wear rate following a change in sliding direction

open access: yes, 2010
The patient demographic for total joint replacement is becoming younger and more active leading to increased performance expectations [1]. To develop new products that meet these demands, computer simulations that predict wear are emerging as potential ...
Taylor, M.   +5 more
core   +1 more source

Can Unilateral Strength Training Optimize Change of Direction Mechanics and Mitigate Anterior Cruciate Ligament Injury Risk in Female Soccer Players? A Preliminary Pre–Post Intervention Study

open access: yesSports
Background: Anterior cruciate ligament (ACL) injuries are a major concern in female soccer players, with change of direction (COD) movements being a key contributor to non-contact injuries.
Alice Rogalski   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Arts District Foundation and Artpicks—City Arts Program presents Voices of Change

open access: yes, 1985
A concert recording of the July 20, 1985 performance of the Voices of Change music ensemble. The Voices of Change music ensemble performs works by 20th and 21st century composers.
Voices of Change (Musical group)
core  

Effects of Sidestep Exercise with Elastic Bands on Multidirectional Speed Abilities and Navicular Drop in Young Male Football Players: A Randomized Cross-Over Trial

open access: yesApplied Sciences
The current study aimed to assess the effect of including the lateral-step or sidestep exercise with elastic bands on multidirectional speed abilities (linear, change of direction, and curve sprinting) and navicular drop and to know the impact of ...
Juan L. Núñez-González   +4 more
doaj   +1 more source

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