Results 91 to 100 of about 3,756,943 (255)

Impacts of duration and intensity of artificial light at night on life history, mating, food consumption, and chemical surface profiles of a leaf beetle species

Basic and Applied Ecology
Artificial light at night (ALAN) is a global change factor of rapidly growing importance. It has been linked to various changes in species physiology, behaviour, communication, and life history. While most studies compared absence vs.
Sandra Regina Lang, Oskar Scherer, Rabea Schweiger, Caroline Müller   +3 more
doaj   +1 more source

Evolution of population with sexual and asexual reproduction in changing environment

, 2003
Using a lattice model based on Monte Carlo simulations, we study the role of the reproduction pattern on the fate of an evolving population. Each individual is under the selection pressure from the environment and random mutations. The habitat ("climate")
CHANGLIANG YU, Fraser A., HONGBO RUAN, LEI YAO, MINGFENG HE, Muller H. J., Orcal B., Penna T. J. P., Wachter K. W.   +8 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Flood Frequency Analysis of Feilaixia in Beijiang River Based on Empirical Mode Decomposition Reconstruction

Renmin Zhujiang
Based on historical flood data (1764—) and measured flood data (1953—2024), the consistency of floods at Feilaixia Station in Beijiang River was tested using time series diagrams, sliding means, M-K method, and Hurst index.
WANG Jin, LI Xiangjiao, WANG Huan
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Dynamic updating of clinical survival prediction models in a changing environment. [PDF]

Diagn Progn Res, 2023
Tanner KT, Keogh RH, Coupland CAC, Hippisley-Cox J, Diaz-Ordaz K.   +4 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Gregarines impact consumption and development but not glucosinolate metabolism in the mustard leaf beetle

Frontiers in Physiology
Gregarines are usually classified as parasites, but recent studies suggest that they should be viewed on a parasitism-mutualism spectrum and may even be seen as part of the gut microbiota of host insects.
Alessa Barber, Jeanne Friedrichs, Caroline Müller, Caroline Müller   +3 more
doaj   +1 more source