Results 121 to 130 of about 597,437 (258)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Editorial: Fungal-plant interactions in a changing environment: from mutualism to pathogenesis. [PDF]

Front Fungal Biol
Das S, Basu A, Angelini P, Sarkar S.
europepmc   +1 more source

Salpa genome and developmental transcriptome analyses reveal molecular flexibility enabling reproductive success in a rapidly changing environment. [PDF]

Sci Rep, 2023
Castellano KR, Batta-Lona P, Bucklin A, O'Neill RJ.   +3 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Editorial: Floral adaptations and pollinator dynamics in a rapidly changing environment. [PDF]

Front Plant Sci
Lipińska MM, Karremans AP.
europepmc   +1 more source

Oxidation and fragmentation of plastics in a changing environment; from UV-radiation to biological degradation. [PDF]

Sci Total Environ, 2022
Andrady AL, Barnes PW, Bornman JF, Gouin T, Madronich S, White CC, Zepp RG, Jansen MAK.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Changing practice in gastroenterology in a changing environment [PDF]

Clinical Medicine, 2007
openaire   +2 more sources

Analysis of Evolutionary Characteristics of Highest Water Levels in Pearl River Guangzhou Reach under Changing Environments

Renmin Zhujiang
The evolution characteristics of the highest water levels in the Pearl River are of great significance for the planning and design of flood control works in Guangzhou.
WANG Jin, LIANG Yingshan, LIN Kairong
doaj  

Editorial: Ecological and genetic insights into seaweeds’ diversity and adaptation

Frontiers in Marine Science, 2023
Zi-Min Hu, Mahasweta Saha, Chaotian Xie, Yunxiang Mao, Yunxiang Mao, Georgina Wood, Trevor T. Bringloe   +6 more
doaj   +1 more source