Results 131 to 140 of about 750,328 (309)

WQEye (v1): A Python-based software for machine learning-based retrieval of water quality parameters from Sentinel-2 and Landsat-8/9 remote sensing data aided by Google Earth Engine

open access: yesEcological Informatics
Despite substantial progress in Remote Sensing (RS)-based estimation of Water Quality Parameters (WQPs) using Machine Learning (ML) models, there remains a lack of end-to-end software that automates the entire workflow.
Alireza Taheri Dehkordi   +3 more
doaj   +1 more source

Imitators and Optimizers in a Changing Environment [PDF]

open access: yes
We analyze the dynamic interaction between imitation and myopic optimization in an environment of changing marginal payoffs. Focusing on finite irreducible environments, we unfold a trade-off between the degree of interaction and the size of ...
Hehenkamp, Burkhard, Kaarbøe, Oddvar M.
core  

Physiological traits of organisms in a changing environment [PDF]

open access: yes, 2006
Antarctic ecosystems represent one extreme of the continuum of environmental conditions across the planet. To our eyes, the environment appears harsh but, even though terrestrial biological diversity is restricted, a wide range of life is present and ...
Huiskes, A.H.L.   +8 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Professionalism and skills enhancement in the built environment: the role of higher education in a changing policy context in England [PDF]

open access: yes, 2005
Since the election of the Labour Government in 1997 there have been a series of policy initiatives emphasising the importance of co-ordinated and integrated approaches to the delivery of urban regeneration and in particular Sustainable Communities. This
Bailey, Nick
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Evolution Law of Rainfall during "Loong Boat Water" Period in Macao in Past 120 Years

open access: yesRenmin Zhujiang
The term of Loong Boat Water refers to heavy rainfall in South China (Guangdong, Guangxi, and Fujian) during China's Dragon Boat Festival period (late May to mid-June), traditiornally called"Loong Boat Water" in Chinese.
WANG Jin   +3 more
doaj   +2 more sources

Single-occupancy simulator for ambient intelligent environment [PDF]

open access: yes, 2008
In this paper, the simulation of an occupant’s behaviour in a single-occupant ambient intelligent environment is addressed. The algorithm of the simulator is designed flexible enough to accept different environmental profiles including the number of ...
Sherkat, N   +3 more
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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