Results 61 to 70 of about 3,756,943 (255)

Our changing environment [PDF]

open access: yesNature, 1994
BOOK REVIEWS Our changing environment Ralph}. Cicerone Atmospheric change: An Earth system Perspective. By T. E. Graedel and P. J. Crutzen. W. H. Freeman: 1993. Pp. 446. £35.95, $42.95 (hbk); £16.95, $32.95 (pbk). ‘EARTH system science’ is a term being adopted by teachers and researchers who are concerned with more than just oceanography, meteorology ...
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Evolution Law of Rainfall during "Loong Boat Water" Period in Macao in Past 120 Years

open access: yesRenmin Zhujiang
The term of Loong Boat Water refers to heavy rainfall in South China (Guangdong, Guangxi, and Fujian) during China's Dragon Boat Festival period (late May to mid-June), traditiornally called"Loong Boat Water" in Chinese.
WANG Jin   +3 more
doaj   +2 more sources

Learning in a changing environment [PDF]

open access: yes, 2009
Multiple cue probability learning studies have typically focused on stationary environments. We present three experiments investigating learning in changing environments.
Shanks, D.R., Speekenbrink, M.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Beyond the Financial Crisis:Addressing Risk Challenges in a Changing Financial Environment [PDF]

open access: yes, 2009
The Financial Crisis has not only highlighted the importance of addressing issues such as liquidity risk – it has also brought to the fore the need to focus on unregulated instruments such as hedge funds, which are of systemic importance to the financial
Ojo, Mariane.B.
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Changing business environment in Belarus

open access: yesJournal of Geography, Politics and Society, 2019
The paper considers the business environment in the context of socio-economic development of the Republic of Belarus. It is analyzed and evaluated the current state of the Belarusian business in terms of various criteria: activity objectives, ownership ...
Olena Hrechyshkina , Maryia Samakhavets
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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