Results 51 to 60 of about 3,122,392 (352)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Manning roughness coefficient in vegetated open channels
Water Science, 2020 Manning equation is one of the most common equations used in estimating the mean velocity and discharge in open channels. The equation depends on some measured hydraulic parameters as water surface slope and hydraulic radius of open channel cross-section
Mohamed Salah Abd Elmoaty +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On the MIMO Channel Capacity for the Nakagami-$m$ Channel [PDF]
IEEE Transactions on Information Theory, 2007 This paper presents the MIMO channel capacity over the Nakagami-m fading channel. The joint eigenvalue density function of W = HHdagger, where H is the channel matrix, is derived in a closed form in the 2 times 2 case and for integer values of m, as well as for m rarr infin.
Gustavo Fraidenraich +2 more
openaire +3 more sources
, 1991 Signalling is the life-blood of telecommunications and common-channel signalling is the key to providing flexible and cost-effective services to customers.
Manterfield, Richard J. +1 more
core +1 more source
Health Science ReportsBackground and Aims Public attitudes toward medicinal cannabis (MC) remain mixed, particularly in areas with legal access to recreational cannabis (RC).
Thomas A. Clobes +3 more
doaj +1 more source
Continuous glucose monitoring during pregnancy in healthy mice
Scientific Reports, 2021 During pregnancy, metabolic adaptations occur to maintain the balance between maternal and foetal growth, including increased insulin secretion and decreased insulin sensitivity. When the body fails to adjust, gestational diabetes mellitus develops.
Caroline Wuyts +4 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The capacity of a channel with arbitrarily varying channel probability functions and binary output [PDF]
, 1970 Ahlswede R, Wolfowitz J. The capacity of a channel with arbitrarily varying channel probability functions and binary output. Zeitschrift für Wahrscheinlichkeitstheorie und verwandte Gebiete.
Ahlswede, Rudolf, Wolfowitz, J.
core +1 more source