Results 61 to 70 of about 1,342,821 (331)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Mutual Information and Multi-Agent Systems

Entropy, 2022
We consider the use of Shannon information theory, and its various entropic terms to aid in reaching optimal decisions that should be made in a multi-agent/Team scenario.
Ira S. Moskowitz, Pi Rogers, Stephen Russell   +2 more
doaj   +1 more source

Exploiting entanglement in communication channels with correlated noise

, 2003
We develop a model for a noisy communication channel in which the noise affecting consecutive transmissions is correlated. This model is motivated by fluctuating birefringence of fiber optic links.
A. Ghatak, A. S. Holevo, Andrzej Dragan, D. M. Brink, Jonathan Ball, Konrad Banaszek, M. A. Nielsen, M. Born   +7 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Optimum response scheme of intrusion detection based on information theory

Tongxin xuebao, 2020
Intrusion detection system (IDS) often inevitably presents major security risks caused by FPs and FNs.However,at present,an effective solution has not been found.In order to solve this problem,an optimal response model of intrusion detection based on ...
Youliang TIAN, Yulong WU, Qiuxian LI
doaj  

The strong converse theorem for the product-state capacity of quantum channels with ergodic Markovian memory [PDF]

, 2016
Establishing the strong converse theorem for a communication channel confirms that the capacity of that channel, that is, the maximum achievable rate of reliable information communication, is the ultimate limit of communication over that channel. Indeed,
Dorlas, Tony, Morgan, Ciara
core   +1 more source

Tema Con Variazioni: Quantum Channel Capacity

, 2003
Channel capacity describes the size of the nearly ideal channels, which can be obtained from many uses of a given channel, using an optimal error correcting code.
Ash R B, Barnum H, Barnum H, Bennett C H, Bjelakovi? I Krüger T Siegmund-Schultze R Szko?a A, Bjelakovi? I Krüger T Siegmund-Schultze R Szko?a A, Bjelakovi? I Siegmund-Schultze R, Bowen G, Bratteli O, Davies E B, Dennis Kretschmann, Devetak I, Devetak I Harrow A W Winter A, Devetak I Winter A, Devetak I Winter A, DiVincenzo D P, Hamada M, Hamada M, Hamada M, Harrow A, Holevo A S, Horodecki M, Horodecki M Shor P W Ruskai M B, Ingham A E, Keyl M, Keyl M, Knill E, Kraus K, Lloyd S, McEliece R J, Nielsen M A, Ogawa T Nagaoka H, Paulsen V I, Reed M, Reimpell M Werner R F, Reinhard F Werner, Ruskai M B, Schumacher B, Shannon C E, Shor P W, Shor P W, Shor P W, Werner R F, Werner R F   +43 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Dependence of the performance of the reclaiming sewer cleaner with rigid guides from interchangeable bucket tools capabilities

Овощи России, 2022
Relevance. Cleaning of reclamation channels is a very relevant event. The need to clean the canals and maintain them in working condition becomes obvious during the flood period, when it is necessary to remove excess water.
Kh. A. Abdulmazhidov
doaj   +1 more source

The capacity region of broadcast channels with intersymbol interference and colored Gaussian noise [PDF]

, 2001
We derive the capacity region for a broadcast channel with intersymbol interference (ISI) and colored Gaussian noise under an input power constraint. The region is obtained by first defining a similar channel model, the circular broadcast channel, which ...
Effros, Michelle, Goldsmith, Andrea J.
core