Results 41 to 50 of about 1,926,748 (272)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Entropy, 2019 This paper investigates the minimum mean square error (MMSE) of communicating a pair of Gaussian sources over a a bandwidth-matched Gaussian multiple-access channel with block Rayleigh fading in the absence of channel state information (CSI) at the ...
Chathura Illangakoon, Pradeepa Yahampath
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A survey on deep learning based joint source-channel coding
Dianxin kexue, 2020 Classical information theory shows that separate source-channel coding is asymptotically optimal over a point-to-point channel.As modern communication systems are becoming more sensitive to delays and bandwidth,it becomes difficult to adopt the ...
Tianjie MU +6 more
doaj +2 more sources
Dense coding capacity of a quantum channel
Physical Review Research, 2020 We consider the fundamental protocol of dense coding of classical information assuming that noise affects both the forward and backward communication lines between Alice and Bob.
Riccardo Laurenza +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Study on the Key Technology of Image Transmission Mechanism Based on Channel Coding Ghost Imaging
IEEE Photonics Journal, 2018 Based on the analysis of the algorithm of ghost imaging and channel coding transmission, this paper combines the error detection and correction function of channel coding and accurate transmission of ghost imaging to complete image coding transmission ...
Leihong Zhang, Ye Hualong, Dawei Zhang
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Distributed Joint Source-Channel Coding-Based Adaptive Dynamic Network Coding
IEEE Access, 2020 Distributed Source Coding (DSC) schemes rely on separate encoding but joint decoding of statistically dependent sources, which exhibit correlation. More specifically, Distributed Joint Source-Channel coding (DJSC) is associated with the scenario, where ...
Abdulah Jeza Aljohani, Soon Xin Ng
doaj +1 more source