Results 61 to 70 of about 1,926,748 (272)
We describe a multilayered video transport scheme for wireless channels capable of adapting to channel conditions in order to maximize end-to-end quality of service (QoS).
James W. Modestino, Yong Pei
doaj +2 more sources
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
A unary error correction code for the near-capacity joint source and channel coding of symbol values from an infinite set [PDF]
A novel Joint Source and Channel Code (JSCC) is proposed, which we refer to as the Unary Error Correction (UEC) code. Unlike existing JSCCs, our UEC facilitates the practical encoding of symbol values that are selected from a set having an infinite ...
Wang, T. +3 more
core +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Joint source-coding, channel-coding and modulation schemes based on Variable Length Codes (VLCs), Trellis Coded Modulation (TCM), Turbo TCM (TTCM), Bit-Interleaved Coded Modulation (BICM) and iteratively decoded BICM (BICM-ID) schemes are proposed.
Yang, L.-L. +4 more
core +1 more source
Polar codes for channel and source coding
The two central topics of information theory are the compression and the transmission of data. Shannon, in his seminal work, formalized both these problems and determined their fundamental limits. Since then the main goal of coding theory has been to find practical schemes that approach these limits.
openaire +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
A Network-Coding Aided Road-Map of Large-Scale Near-Capacity Cooperative Communications
In the paper, we present a road-map towards a near-capacity large-scale multi-user cooperativecommunications (NLMC) system, where all the evolution paths converge to the construction of the NLMC system.
Hung Viet Nguyen +4 more
doaj +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source

