Results 51 to 60 of about 1,926,748 (272)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Near-Capacity Network Coding for Cooperative Multi-User Communications [PDF]

open access: yes, 2011
In this contribution, we investigate Near-Capacity Multiuser Network-coding (NCMN) based systems using an Irregular Convolutional Code, a Unity-Rate Code and M-ary Phase-Shift Keying.
Joao Luiz Rebelatto   +9 more
core   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Capacity-achieving coding for cellular downlink with bidirectional communication

open access: yes, 2010
In this work we provide capacity achieving coding strategies for the cellular downlink with three users where two users want to communicate with each other.
Do, Hieu,   +2 more
core   +7 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

An Introduction to Distributed Channel Coding

open access: yes, 2014
This chapter provides an introductory survey on distributed channel coding techniques for relay networks. The main focus is on decode-and-forward relaying for the basic three-node relay channel.
Alexandre Graell i Amat   +6 more
core   +1 more source

Channels with arbitrarily varying channel probability functions in the presence of noiseless feedback [PDF]

open access: yes, 1973
Ahlswede R. Channels with arbitrarily varying channel probability functions in the presence of noiseless feedback. Zeitschrift für Wahrscheinlichkeitstheorie und verwandte Gebiete.
Ahlswede, Rudolf
core   +1 more source

Joint source-channel coding for image transmission based on best wavelet packet

open access: yesTongxin xuebao, 2012
A novel joint source/channel image coding algorithm was proposed based on the best wavelet packet in a rate-distortion sense.Different from other wavelet packet image coding,the channel and the channel code information were introduced to the source ...
Jun-hong CHEN, Qin-yu ZHANG
doaj   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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