Results 101 to 110 of about 1,383,477 (261)

Testing for Violations of Microscopic Reversibility in ATP-Sensitive Potassium Channel Gating

, 2016
In pancreatic β cells, insulin secretion is tightly controlled by the cells’ metabolic state via the ATP-sensitive potassium (KATP) channel. ATP is a key mediator in this signaling process, where its role as an inhibitor of KATP channels has been ...
Kee-Hyun Choi (160985), Mathew Tantama (2185042), Stuart Licht (160989)   +2 more
core   +1 more source

Memristive‐Gated RC‐Delay Synaptic Transistors for Time‐Encoded Analog in‐Memory Computing

Advanced Functional Materials, EarlyView.
A Memristive‐Gated Transistor for Time‐Encoded Analog In‐Memory Computing — By exploiting the RC delay of a self‐rectifying interface‐type memristor, nonlinear I–V distortion is structurally bypassed, enabling 3‐bit nonvolatile memory, spike‐timing‐based analog encoding, and hardware‐calibrated reservoir‐computing validation within a unified device ...
Yun‐Seo Shin, Eunjoo Yoo, Ki‐Hoon Son, Hyun‐Sik Kim, Dae‐Hee Han, Jeong Hyeon Son, Seung Hwan Lee, Hong‐Sub Lee   +7 more
wiley   +1 more source

The First Extracellular Domain Plays an Important Role in Unitary Channel Conductance of Cx50 Gap Junction Channels.

PLoS ONE, 2015
Gap junction (GJ) channels provide direct passage for ions and small molecules to be exchanged between neighbouring cells and are crucial for many physiological processes.
Xiaoling Tong, Hiroshi Aoyama, Swathy Sudhakar, Honghong Chen, Brian H Shilton, Donglin Bai   +5 more
doaj   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Advanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan, Hocheon Yoo, Benoît H. Lessard, Ioannis Kymissis, Chang‐Hyun Kim   +4 more
wiley   +1 more source

Bio‐Inspired Artificial Ionic Mechanoreceptor

Advanced Functional Materials, EarlyView.
A skin‐inspired artificial mechanoreceptor based on ionic interactions is presented for biomimetic tactile sensing. Pressure‐driven ionic redistribution within microfluidic channels generates a self‐powered electrical signal without external bias. The generated waveform exhibits mechanoreceptor‐like temporal features, including overshoot and undershoot,
Mohammad Akbari, Jeppe Don, Lasse A. N. Pedersen, John Noee, Rassoul Tabassian   +4 more
wiley   +1 more source

Role of the S6 C-terminus in KCNQ1 channel gating

, 2007
Co-assembly of KCNQ1 alpha-subunits with KCNE1 beta-subunits results in the channel complex underlying the cardiac I-Ks current in vivo. Like other voltage-gated K+ channels, KCNQ1 has a tetrameric configuration.
Inge R. Boulet, Adam L. Raes, Snyders, Dirk J., Labro, Alain J, Raes, Adam L., Dirk J. Snyders, Boulet, Inge R., Alain J. Labro, Labro, Alain J.   +8 more
core   +1 more source

Gating modulation of the KCNQ1 channel by KCNE proteins studied by voltage-clamp fluorometry

Biophysics and Physicobiology, 2019
The KCNQ1 channel is a voltage-dependent potassium channel and is ubiquitously expressed throughout the human body including the heart, lung, kidney, pancreas, intestine and inner ear.
Koichi Nakajo
doaj   +1 more source

Microscale Patterning of Ultrahigh‐Viscosity Metallic‐Polymer Composites via Embedded Droplet Writing

Advanced Functional Materials, EarlyView.
A hybrid additive manufacturing platform integrates direct droplet writing of metallic composite with VAT photopolymerization to fabricate architected soft magnetic composites. This approach enables microscale patterning of high‐viscosity materials for programmable actuators, adaptive fluidic devices, and switchable adhesives, offering tunable ...
Yeowon Yoon, Jian Ni, Sungmo Park, Yang Xu, Yong Chen   +4 more
wiley   +1 more source

Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels1 are essential for pacemaking activity and neural signalling2,3. Drugs inhibiting HCN1 are promising candidates for management of neuropathic pain4 and epileptic seizures5.
Wu, Xiaoan,, Accardi, Alessio,, Cunningham, Kevin P.,, Nimigean, Crina M, Goldstein, Peter A.,, Kim, Elizabeth D.,, Wu, Xiaoan, Larsson, H Peter, Perez, Marta E.,, Larsson, H. Peter,, Lee, Sangyun, Kim, Elizabeth D, Perez, Marta E, Di Zanni, Eleonora,, Accardi, Alessio, Tibbs, Gareth R.,, Di Zanni, Eleonora, Lee, Sangyun,, Tibbs, Gareth R, Cunningham, Kevin P, Goldstein, Peter A, Nimigean, Crina M.,, H. Peter Larsson, Sangyun Lee, Marta E. Perez, Alessio Accardi, Peter A. Goldstein, Crina M. Nimigean, Gareth R. Tibbs, Kevin P. Cunningham, Xiaoan Wu, Eleonora Di Zanni, Elizabeth D. Kim   +32 more
core   +1 more source

Improving Out-of-Distribution Robustness for Wheat Head Detection: A Lightweight Modified YOLOv13 Approach

Agronomy
Wheat head detection is a critical component in high-throughput phenotyping, holding significant application value for wheat yield estimation and breeding analysis.
Peng Hui, Liyuan Zhang, Qingzhen Zhu
doaj   +1 more source