Results 1 to 10 of about 498,634 (151)
Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
The cation-permeable TRPV2 channel is important for cardiac and immune cell function. Cannabidiol (CBD), a non-psychoactive cannabinoid of clinical relevance, is one of the few molecules known to activate TRPV2.
Aaron Gochman +5 more
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The processing of incoming sensory information can be differentially affected by varying levels of α-power in the electroencephalogram (EEG). A prominent hypothesis is that relatively low prestimulus α-power is associated with improved perceptual ...
Lars T. Boenke +9 more
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A long-standing goal in protein science and clinical genetics is to develop quantitative models of sequence, structure, and function relationships to understand how mutations cause disease.
Willow Coyote-Maestas +3 more
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Ion-ing out the genetic variants of Kir2.1
Deep mutational scanning provides new insights into how mutations alter the expression and activity of the potassium ion channel Kir2.1, which is associated with many diseases.
Braden S Fallon, Justin G English
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Topography and motion of acid-sensing ion channel intracellular domains
Acid-sensing ion channels (ASICs) are trimeric cation-selective channels activated by decreases in extracellular pH. The intracellular N and C terminal tails of ASIC1 influence channel gating, trafficking, and signaling in ischemic cell death.
Tyler Couch +5 more
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Structures of the trimeric acid-sensing ion channel have been solved in the resting, toxin-bound open and desensitized states. Within the extracellular domain, there is little difference between the toxin-bound open state and the desensitized state.
Matthew L. Rook +3 more
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Detection and monitoring of minimal residual disease (MRD) are essential components of programmed therapy.They are crucial for the choice of treatment strategy and for prognostic purposes practically in all hematologic diseases.
I. V. Galtseva +4 more
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IntroductionPatients treatment compliance increases during free-breathing (FB) treatment, taking generally less time and fatigue with respect to deep inspiration breath-hold (DIBH).
Matteo Galetto +13 more
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Bat use of abandoned mines throughout Nevada
Abandoned mines offer important roosting habitat for several species of bats throughout the western United States. Currently, abandoned mine reclamation programs are tasked with closing abandoned mines to ameliorate safety, health, and environmental ...
Megan L. Moran +3 more
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Entropy measures and predictive recognition as mirrored in gating and lexical decision over multimorphemic Hungarian noun forms [PDF]
Our paper is an attempt to indicate the relevance of information theoretical accounts to understand word recognition and morphological processing in Hungarian, along with other studies using more traditional predictors like linear position and ...
Pléh Csaba +4 more
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