Results 1 to 10 of about 224,217 (169)
Journal of General Physiology, 2018 Many membrane proteins sense the voltage across the membrane where they are inserted, and their function is affected by voltage changes. The voltage sensor consists of charges or dipoles that move in response to changes in the electric field, and their movement produces an electric current that has been called gating current.
Francisco Bezanilla
exaly +3 more sources
Cannabidiol sensitizes TRPV2 channels to activation by 2-APB
eLife, 2023 The cation-permeable TRPV2 channel is important for cardiac and immune cell function. Cannabidiol (CBD), a non-psychoactive cannabinoid of clinical relevance, is one of the few molecules known to activate TRPV2.
Aaron Gochman +5 more
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Frontiers in Computational Neuroscience, 2023 The processing of incoming sensory information can be differentially affected by varying levels of α-power in the electroencephalogram (EEG). A prominent hypothesis is that relatively low prestimulus α-power is associated with improved perceptual ...
Lars T. Boenke +9 more
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eLife, 2022 A long-standing goal in protein science and clinical genetics is to develop quantitative models of sequence, structure, and function relationships to understand how mutations cause disease.
Willow Coyote-Maestas +3 more
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Ion-ing out the genetic variants of Kir2.1
eLife, 2022 Deep mutational scanning provides new insights into how mutations alter the expression and activity of the potassium ion channel Kir2.1, which is associated with many diseases.
Braden S Fallon, Justin G English
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Topography and motion of acid-sensing ion channel intracellular domains
eLife, 2021 Acid-sensing ion channels (ASICs) are trimeric cation-selective channels activated by decreases in extracellular pH. The intracellular N and C terminal tails of ASIC1 influence channel gating, trafficking, and signaling in ischemic cell death.
Tyler Couch +5 more
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ACM SIGGRAPH 2009 Emerging Technologies, 2009 This project associates multi-camera 3D modeling, physical simulation, and tracked head-mounted displays for a strong full-body immersion and presence in virtual worlds. Three-dimensional modeling is based on the EPHV algorithm, which provides an exact geometrical surface according to input data. The geometry enables computation of full-body collisions
Petit, Benjamin +3 more
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Frontiers in Cellular Neuroscience, 2021 Structures of the trimeric acid-sensing ion channel have been solved in the resting, toxin-bound open and desensitized states. Within the extracellular domain, there is little difference between the toxin-bound open state and the desensitized state.
Matthew L. Rook +3 more
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Design of Gates for Quantum Computation: The NOT Gate [PDF]
International Journal of Modern Physics B, 1997 We offer an alternative to the conventional network formulation of quantum computing. We advance the analog approach to quantum logic gate/circuit construction. As an illustration, we consider the spatially extended NOT gate as the first step in the development of this approach.
Mozyrsky, Dima +2 more
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Клиническая онкогематология, 2021 Detection and monitoring of minimal residual disease (MRD) are essential components of programmed therapy.They are crucial for the choice of treatment strategy and for prognostic purposes practically in all hematologic diseases.
I. V. Galtseva +4 more
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