Results 31 to 40 of about 1,212,232 (342)

Gating mechanisms of acid sensing ion channels

open access: yesNature, 2018
Acid-sensing ion channels (ASICs) are trimeric, proton-gated and sodium-selective members of the epithelial sodium channel/degenerin (ENaC/DEG) superfamily of ion channels and are expressed throughout vertebrate central and peripheral nervous systems ...
N. Yoder, C. Yoshioka, E. Gouaux
semanticscholar   +1 more source

Photovoltaic effect in few-layer black phosphorus PN junctions defined by local electrostatic gating [PDF]

open access: yesNature Communications, 2014
In conventional photovoltaic solar cells, photogenerated carriers are extracted by the built-in electric field of a semiconductor PN junction, defined by ionic dopants.
M. Buscema   +4 more
semanticscholar   +1 more source

Consonant Recognition Using Coarticulatory Cues in Individuals with Normal Hearing and Sensorineural Hearing Loss

open access: yesJournal of Indian Speech Language & Hearing Association, 2021
Background and Objectives The study investigated the role of coarticulatory cues in the perception of consonants in Malayalam and its temporal window. It also compared normal hearing individuals and individuals with sensorineural hearing loss (SNHL) for ...
Dhanya Mohan, Sandeep Maruthy
doaj   +1 more source

Optically gated beating-heart imaging [PDF]

open access: yes, 2014
The constant motion of the beating heart presents an obstacle to clear optical imaging, especially 3D imaging, in small animals where direct optical imaging would otherwise be possible.
Taylor, Jonathan M.
core   +2 more sources

Structures and gating mechanism of human TRPM2

open access: yesScience, 2018
Architecture of the human TRPM2 channel Adenosine diphosphate–ribose (ADPR) mediates calcium (Ca2+) release by activating the transient receptor potential melastatin 2 (TRPM2) channel.
Longfei Wang   +5 more
semanticscholar   +1 more source

Molecular Dynamics Simulations of a Cytochrome P450 from Tepidiphilus thermophilus (P450-TT) Reveal How Its Substrate-Binding Channel Opens

open access: yesMolecules, 2021
Cytochrome P450s (P450) are important enzymes in biology with useful biochemical reactions in, for instance, drug and xenobiotics metabolisms, biotechnology, and health.
Abayomi S. Faponle   +3 more
doaj   +1 more source

Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling

open access: yesNature Communications, 2019
Potassium channels are presumed to have two allosterically coupled gates, the activation gate and the selectivity filter gate, that control channel opening, closing, and inactivation.
Wojciech Kopec   +2 more
semanticscholar   +1 more source

Gating currents indicate complex gating of voltage-gated proton channels [PDF]

open access: yesProceedings of the National Academy of Sciences, 2018
The voltage-gated proton channel (HV1) is a unique molecule that resides at the interface between ion channels and bioenergetic molecules that use proton gradients to store or transduce energy. HV1 plays key roles in the health and disease of diverse tissues and species (1). Important information regarding the physical components of ion-channel gating (
openaire   +2 more sources

Phosphorylation-Dependent Regulation of Mammalian Aquaporins

open access: yesCells, 2019
Water homeostasis is fundamental for cell survival. Transport of water across cellular membranes is governed by aquaporins—tetrameric integral membrane channels that are highly conserved throughout the prokaryotic and eukaryotic kingdoms.
Veronika Nesverova   +1 more
doaj   +1 more source

Development and validation of a matlab software program for decoding the treatment errors in real-time position management™ Gating-generated breathing trace

open access: yesJournal of Medical Physics, 2020
Introduction: The Real-time Position Management™ (RPM) is used as a motion management tool to reduce normal tissue complication. However, no commercial software is available to quantify the “beam-on” errors in RPM-generated breathing traces.
Naveen Kumawat   +7 more
doaj   +1 more source

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