Results 91 to 100 of about 24,272,839 (333)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Comprehensive Survey on UAV Communication Channel Modeling

open access: yesIEEE Access, 2019
Unmanned aerial vehicles (UAVs) have stroke great interested both by the academic community and the industrial community due to their diverse military applications and civilian applications.
Chaoxing Yan   +3 more
semanticscholar   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

ROUTE SIMULATION TRANSPORTS POLYGONAL SECTION CANAL WITH COMPLEX PROGRAM

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2016
The paper considers the problem of modeling the optimal route of the canal conveying polygonal cross-sectional shape, which extends into the recess without artificially mount.
G. A. Alibekov
doaj   +1 more source

Device modeling of long-channel nanotube electro-optical emitter

open access: yes, 2005
We present a simple analytic model of nanotube electro-optical emitters, along with improved experimental measurements using PMMA-passivated devices with reduced hysteresis.
Avouris, Phaedon   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Ray-Based Modeling of Directional Millimeter-Wave V2V Transmissions in Highway Scenarios

open access: yesIEEE Access, 2020
Due to the need for larger bandwidth, future mobile networks may primarily operate over millimeter-wave (mmWave) bands. In this regard, one of the central research topics today is mmWave channel modeling.
Yekaterina Sadovaya   +7 more
doaj   +1 more source

Analytical Model for Outdoor Millimeter Wave Channels using Geometry-Based Stochastic Approach

open access: yes, 2016
The severe bandwidth shortage in conventional microwave bands has spurred the exploration of the millimeter wave (MMW) spectrum for the next revolution in wireless communications.
Li, Yonghui   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy