Results 171 to 180 of about 18,335 (296)

Optogenetic stimulation of lateral amygdala input to posterior piriform cortex modulates single-unit and ensemble odor processing

Frontiers in Neural Circuits, 2015
Olfactory information is synthesized within the olfactory cortex to provide not only an odor percept, but also a contextual significance that supports appropriate behavioral response to specific odor cues.
Benjamin eSadrian, Benjamin eSadrian, Donald A Wilson, Donald A Wilson   +3 more
doaj   +1 more source

Kalium channelrhodopsins effectively inhibit neurons

Nature Communications
AbstractThe analysis of neural circuits has been revolutionized by optogenetic methods. Light-gated chloride-conducting anion channelrhodopsins (ACRs)—recently emerged as powerful neuron inhibitors. For cells or sub-neuronal compartments with high intracellular chloride concentrations, however, a chloride conductance can have instead an activating ...
Stanislav Ott, Sangyu Xu, Nicole Lee, Ivan Hong, Jonathan Anns, Danesha Devini Suresh, Zhiyi Zhang, Xianyuan Zhang, Raihanah Harion, Weiying Ye, Vaishnavi Chandramouli, Suresh Jesuthasan, Yasunori Saheki, Adam Claridge-Chang   +13 more
openaire   +4 more sources

Leaky expression of channelrhodopsin-2 (ChR2) in Ai32 mouse lines

PLoS ONE, 2019
Optogenetics enables the selective activation of genetically-targeted neuronal populations using light-sensitive ion channels. Genetic strategies using Cre-dependent mouse strains, especially the Ai32 line expressing Channelrhodopsin (ChR2)-EYFP fusion ...
Arthi Prabhakar, Dragan Vujovic, L. Cui, William P Olson, Wenqin Luo   +4 more
semanticscholar   +1 more source

Dissecting inhibitory brain circuits with genetically-targeted technologies

Frontiers in Neural Circuits, 2014
The evolution of genetically targeted tools has begun to allow us to dissect anatomically and functionally heterogeneous interneurons, and to probe circuit function from synapses to behavior.
Dona Kim Murphey, Alexander M Herman, Benjamin R. Arenkiel, Benjamin R. Arenkiel, Benjamin R. Arenkiel   +4 more
doaj   +1 more source

Escape Behavior Elicited by Single, Channelrhodopsin-2-Evoked Spikes in Zebrafish Somatosensory Neurons [PDF]

, 2008
Adam D. Douglass, Sebastian Kraves, Karl Deisseroth, Alexander F. Schier, Florian Engert   +4 more
openalex   +1 more source

Formation Mechanism of Ion Channel in Channelrhodopsin-2: Molecular Dynamics Simulation and Steering Molecular Dynamics Simulations

International Journal of Molecular Sciences, 2019
Channelrhodopsin-2 (ChR2) is a light-activated and non-selective cationic channel protein that can be easily expressed in specific neurons to control neuronal activity by light.
Ting Yang, Wenying Zhang, Jie Cheng, Yanhong Nie, Qi Xin, Shuai Yuan, Y. Dou   +6 more
semanticscholar   +1 more source

Optogenetic dissection of neuronal circuits in zebrafish using viral gene transfer and the Tet system

Frontiers in Neural Circuits, 2009
The conditional expression of transgenes at high levels in sparse and specific populations of neurons is important for high-resolution optogenetic analyses of neuronal circuits.
Peixin Zhu, Yuichi Narita, Sebastian T Bundschuh, Otto Fajardo, Yan-Ping Zhang Schärer, Bidisha Chattopadhyaya, Estelle Arn Bouldoires, Anna E Stepien, Anna E Stepien, Karl Deisseroth, Silvia Arber, Silvia Arber, Rolf Sprengel, Filippo M Rijli, Rainer W Friedrich   +14 more
doaj   +1 more source

In-Depth Activation of Channelrhodopsin 2-Sensitized Excitable Cells with High Spatial Resolution Using Two-Photon Excitation with a Near-Infrared Laser Microbeam [PDF]

, 2008
Samarendra Mohanty, Rainer K. Reinscheid, Xiaobin Liu, Naoe Okamura, Tatiana B. Krasieva, Michael W. Berns   +5 more
openalex   +1 more source

Channelrhodopsin-2 (ChR2) [PDF]

, 2008

openalex   +1 more source

Regulated peristalsis into the acidic region of the _Drosophila_ larval midgut is controlled by a novel component of the Autonomic Nervous System [PDF]

, 2009
The underlying cellular and molecular mechanisms that regulate and coordinate critical physiological processes such as peristalsis are complex, often cryptic, and involve the integration of multiple tissues and organ systems within the organism.
Brooke Ann Johnson, Dennis Richard LaJeunesse, Grzegorz Zapotoczny, Jason Presnell, Kathleen K. Catignas   +4 more
core   +1 more source