Results 81 to 90 of about 17,118 (247)
Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance
Advanced Science, EarlyView.DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin +15 more
wiley +1 more source
Optogenetic Generation of Neural Firing Patterns with Temporal Shaping of Light Pulses
Photonics, 2023 The fundamental process of information processing and memory formation in the brain is associated with complex neuron firing patterns, which can occur spontaneously or be triggered by sensory inputs.
Himanshu Bansal, Gur Pyari, Sukhdev Roy
doaj +1 more source
Exploring adult hippocampal neurogenesis using optogenetics [PDF]
, 2018 In the 1980s, it was widely accepted that new neurons are continuously generated in the dentate gyrus of the mammalian hippocampus. Since its acceptance, researchers have employed various techniques and behavioral paradigms to study the proliferation ...
Pinardo, Heinrich
core
A history of optogenetics: the development of tools for controlling brain circuits with light [PDF]
, 2011 Understanding how different kinds of neuron in the brain work together to implement sensations, feelings, thoughts, and movements, and how deficits in specific kinds of neuron result in brain diseases, has long been a priority in basic and clinical ...
Boyden, Edward Stuart
core +2 more sources
Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation
Advanced NanoBiomed Research, EarlyView.This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley +1 more source
Molecular mechanism of channelrhodopsin
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018 The discovery of channelrhodopsins introduced a new class of ion channels whose conductance can be remotely controlled by light, the feature that founded optogenetics. To explore the connection between the gating mechanism and the influx and efflux of water molecules in channelrhodopsin-2 (ChR2), we have integrated light-induced time-resolved infrared ...
Heberle, J. +6 more
openaire +2 more sources
Modeling Interference-Free Neuron Spikes with Optogenetic Stimulation [PDF]
, 2019 This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W. +3 more
core +2 more sources
Epilepsia Open, EarlyView.Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley +1 more source
Optogenetic dissection of amygdala functioning
Frontiers in Behavioral Neuroscience, 2014 Studies of amygdala functioning have occupied a significant place in the history of understanding how the brain controls behavior and cognition. Early work on the amygdala placed this small structure as a key component in the regulation of emotion and ...
Ryan eLalumiere
doaj +1 more source
Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues
Small Methods, EarlyView.This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley +1 more source