Results 81 to 90 of about 16,974 (201)
Identifying specific prefrontal neurons that contribute to autism-associated abnormalities in physiology and social behavior. [PDF]
, 2017 Functional imaging and gene expression studies both implicate the medial prefrontal cortex (mPFC), particularly deep-layer projection neurons, as a potential locus for autism pathology.
Brumback, AC +9 more
core +1 more source
The power of ionic movements in plants
New Phytologist, EarlyView.Summary The movement of ion‐driven electrogenic events known as plant action potentials in the Venus flytrap Dionaea muscipula has first been recognized in Darwin's time. Besides electrophysiological techniques making use of current‐ and voltage‐recording electrodes, today an ever‐growing spectrum of tools has become available, that report online ...
Rainer Hedrich, Ines Kreuzer
wiley +1 more source
Principles of Optogenetic Methods and Their Application to Cardiac Experimental Systems
Frontiers in Physiology, 2019 Optogenetic techniques permit studies of excitable tissue through genetically expressed light-gated microbial channels or pumps permitting transmembrane ion movement.
Emily A. Ferenczi +3 more
doaj +1 more source
Light and pH-induced Changes in Structure and Accessibility of Transmembrane Helix B and Its Immediate Environment in Channelrhodopsin-2 [PDF]
, 2016 A variant of the cation channel channelrhodopsin-2 from Chlamydomonas reinhardtii (CrChR2) was selectively labeled at position Cys-79 at the end of the first cytoplasmic loop and the beginning of transmembrane helix B with the fluorescent dye ...
Alexiev, Ulrike +7 more
core +1 more source
Models of cardiomyocyte–non‐myocyte electrical interactions
The Journal of Physiology, EarlyView.Abstract figure legend Cardiomyocyte–non‐myocyte (CM–NM) electrotonic coupling. Left: conceptual contact‐based interactions between CM and other NM via connexin (Cx) proteins. Three basic scenarios are proposed: (i) ‘zero‐sided coupling’ where there are no electrical connections between CM and NM, (ii) ‘single‐sided coupling’ where NM are connected to ...
Ana Simon‐Chica +2 more
wiley +1 more source
Modeling Interference-Free Neuron Spikes with Optogenetic Stimulation [PDF]
, 2019 This paper predicts the ability to externally control the firing times of a cortical neuron whose behavior follows the Izhikevich neuron model. The Izhikevich neuron model provides an efficient and biologically plausible method to track a cortical neuron'
Eckford, Andrew W. +3 more
core +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu +2 more
wiley +1 more source
Frontiers in Neural Circuits, 2013 Proper brain function relies on exquisite balance between excitation and inhibition, where inhibitory circuits play fundamental roles towards sculpting principle neuron output and information processing.
Longwen eHuang +3 more
doaj +1 more source
Neuromodulation: present and emerging methods. [PDF]
, 2014 Neuromodulation has wide ranging potential applications in replacing impaired neural function (prosthetics), as a novel form of medical treatment (therapy), and as a tool for investigating neurons and neural function (research).
Constandinou, TG +3 more
core +1 more source
Optimal neuromuscular performance requires motor neuron phosphagen kinases
The Journal of Physiology, EarlyView.Abstract figure legend Motor neuron (MN) terminals in fruit flies, mice and humans contain phosphagen kinases, a key enzyme in their energy storage and buffering system. Here we knocked down the primary phosphagen kinase in fruit fly larvae (arginine kinase 1 (ArgK1)) but were surprised to find that MN endurance was unaffected.
Karlis A. Justs +10 more
wiley +1 more source