Results 101 to 110 of about 37,307 (249)

Optimizing a PCR protocol for cpn60-based microbiome profiling of samples variously contaminated with host genomic DNA. [PDF]

open access: yes, 2015
The current recommended protocol for chaperonin-60 (cpn60) universal target based microbiome profiling includes universal PCR of microbiome samples across an annealing temperature gradient to maximize the diversity of sequences amplified.
Chaban, B   +3 more
core   +1 more source

The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction

open access: yesScientific Reports, 2017
The eukaryotic chaperonin CCT (chaperonin containing TCP-1) uses cavities built into its double-ring structure to encapsulate and to assist folding of a large subset of proteins.
B. Sot   +6 more
semanticscholar   +1 more source

The secreted staphylococcal biofilm protein Sbp forms biomolecular condensates in the presence of DNA

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Staphylococcus epidermidis is the leading cause of device‐related infections, primarily due to its ability to form biofilms, surface‐adherent bacterial communities that confer remarkable resistance to antibiotics and host defenses. Small basic protein, Sbp, is a 16‐kDa protein expressed by S.
P. Ethan Adkins   +2 more
wiley   +1 more source

Formation and Function of the Rbl2p-beta-Tubulin Complex [PDF]

open access: yes, 1998
The yeast protein Rbl2p suppresses the deleterious effects of excess beta-tubulin as efficiently as does alpha-tubulin. Both in vivo and in vitro, Rbl2p forms a complex with beta-tubulin that does not contain alpha-tubulin, thus defining a second pool of
Archer, Julie E.   +3 more
core  

Directed transport as a mechanism for protein folding in vivo

open access: yes, 2009
We propose a model for protein folding in vivo based on a Brownian-ratchet mechanism in the multidimensional energy landscape space. The device is able to produce directed transport taking advantage of the assumed intrinsic asymmetric properties of the ...
Alberts B.   +9 more
core   +1 more source

Production of a recombinant form of early pregnancy factor that can prolong allogeneic skin graft survival time in rats [PDF]

open access: yes, 2000
Early pregnancy factor (EPF), an extracellular chaperonin 10 homologue, has immunosuppressive and growth factor properties. In order to carry out more extensive studies on the in vivo characteristics of EPF, a recombinant form of the molecule has been ...
Cassady, A I   +7 more
core   +1 more source

Role of CCT chaperonin in the disassembly of mitotic checkpoint complexes

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance The mitotic checkpoint system has an important role in ensuring correct segregation of chromosomes in mitosis. As long as not all chromosomes are attached correctly to the mitotic spindle, a mitotic checkpoint complex (MCC) is assembled and ...
S. Kaisari   +4 more
semanticscholar   +1 more source

Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
The Antarctic Dietzia and Pusillimonas isolates were tested for bioremediation applications. Genomic analyses revealed the potential to degrade complex organic compounds, potential virulence factors and resistance genes. Physiological assays showed a wide range of adaptation to abiotic factors and sensitivity to different groups of antibiotics ...
Tomasz Krucoń   +4 more
wiley   +1 more source

Die Funktion des Responseregulators ARR2 in der Entwicklung von Arabidopsis thaliana [PDF]

open access: yes, 2004
In dieser Arbeit konnte mittels physiologischer Experimente, Expressionsanalysen, Phosphorylierungsassays und Transaktivierungsanalysen eine komplexe Funktion von ARR2 in verschiedenen Signaltransduktionswegen von Arabidopsis aufgedeckt werden.
Haß, Claudia
core  

ATP binding to a multisubunit enzyme: statistical thermodynamics analysis

open access: yes, 2012
Due to inter-subunit communication, multisubunit enzymes usually hydrolyze ATP in a concerted fashion. However, so far the principle of this process remains poorly understood.
A. Fersht   +3 more
core   +1 more source

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