Results 111 to 120 of about 23,911 (226)

Beyond Folding: The Dual Life of Hsp60 in Tissue Homeostasis and Pathophysiology

Applied Biosciences
The heat shock protein 60 (Hsp60) is a highly conserved molecular chaperonin belonging to the chaperone system, a complex network that maintains proteostasis and regulates numerous cellular processes beyond protein folding.
Giuseppa D’Amico, Melania Ionelia Gratie, Giuseppe Vergilio, Francesco Cappello, Alessandra Maria Vitale   +4 more
doaj   +1 more source

SARS-CoV Regulates Immune Function-Related Gene Expressions in Human Monocytic Cells [PDF]

, 2011
Background: Severe Acute Respiratory Syndrome (SARS) is characterized by acute respiratory distress (ARDS) and pulmonary fibrosis, and the monocyte/macrophage is the key player in the pathogenesis of SARS. Methods: In this study, we ...
Betty A. Wu-Hsieh, Chuan-Liang Kao, Sher Singh, Wan-Jiung(Wan-Chung) Hu, Yu-Ting Yen   +4 more
core   +1 more source

Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring.

Journal of Biological Chemistry, 1992
Chaperonins are thought to participate in the process of protein folding in bacteria and in eukaryotic mitochondria and chloroplasts. While some chaperonins are relatively well characterized, the structures of the mammalian chaperonins are unknown.
P V, Viitanen, G H, Lorimer, R, Seetharam, R S, Gupta, J, Oppenheim, J O, Thomas, N J, Cowan   +6 more
openaire   +2 more sources

Ordered Nanostructures Made Using Chaperonin Polypeptides [PDF]

A recently invented method of fabricating periodic or otherwise ordered nanostructures involves the use of chaperonin polypeptides. The method is intended to serve as a potentially superior and less expensive alternative to conventional lithographic ...
Kagawa, Hiromi, McMillan, Robert, Mogul, Rakesh, Paavola, Chad, Trent, Jonathan   +4 more
core   +1 more source

Omnipresent Maxwell’s demons orchestrate information management in living cells [PDF]

, 2019
The development of synthetic biology calls for accurate understanding of the critical functions that allow construction and operation of a living cell.
Danchin, Antoine, Gregory Boel, Olivier Danot, Victor de Lorenzo, Antoine Danchin   +1 more
core  

Predicting protein function with hierarchical phylogenetic profiles: The Gene3D phylo-tuner method applied to eukaryotic Genomes [PDF]

, 2007
"Phylogenetic profiling'' is based on the hypothesis that during evolution functionally or physically interacting genes are likely to be inherited or eliminated in a codependent manner.
Grant, A, Orengo, CA, Ranea, JAG, Yeats, C   +3 more
core  

Editorial: Type I Chaperonins: Mechanism and Beyond

Frontiers in Molecular Biosciences, 2018
Adina Breiman, Abdussalam Azem
doaj   +1 more source

Theoretical Perspectives on Protein Folding

, 2010
Understanding how monomeric proteins fold under in vitro conditions is crucial to describing their functions in the cellular context. Significant advances both in theory and experiments have resulted in a conceptual framework for describing the folding ...
Hyeon, Changbong, Morrison, Greg, O'Brien, Edward P., Thirumalai, D.   +3 more
core   +1 more source

Correction: Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR. [PDF]

Cell Death Dis, 2019
Lian WS, Ko JY, Chen YS, Ke HC, Wu SL, Kuo CW, Wang FS.   +6 more
europepmc   +1 more source

Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR. [PDF]

Cell Death Dis, 2018
Lian WS, Ko JY, Chen YS, Ke HC, Wu SL, Kuo CW, Wang FS.   +6 more
europepmc   +1 more source