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Heat Shock Proteins and Ferroptosis

open access: yesFrontiers in Cell and Developmental Biology, 2022
Ferroptosis is a new form of regulatory cell death named by Dixon in 2012, which is characterized by the accumulation of lipid peroxides and iron ions. Molecular chaperones are a class of evolutionarily conserved proteins in the cytoplasm. They recognize
Ying Liu   +28 more
doaj   +3 more sources

Heat-Shock Proteins in Neuroinflammation [PDF]

open access: yesFrontiers in Pharmacology, 2019
The heat-shock response, one of the main pro-survival mechanisms of a living organism, has evolved as the biochemical response of cells to cope with heat stress.
Brigitta Dukay   +3 more
doaj   +4 more sources

Heat Shock Proteins as Immunomodulants [PDF]

open access: yesMolecules, 2018
Heat shock proteins (Hsps) are conserved molecules whose main role is to facilitate folding of other proteins. Most Hsps are generally stress-inducible as they play a particularly important cytoprotective role in cells exposed to stressful conditions ...
Tawanda Zininga   +2 more
doaj   +3 more sources

Evaluation of Plasma Heat Shock Protein Levels in Smokers

open access: yesAddicta: The Turkish Journal on Addictions, 2022
This study aims to evaluate the effects of smoking on extracellular heat shock protein levels. Heat shock proteins have been associated with numerous diseases.
Muhammet Kızmaz   +3 more
doaj   +1 more source

Integrative genetic, genomic and transcriptomic analysis of heat shock protein and nuclear hormone receptor gene associations with spontaneous preterm birth

open access: yesScientific Reports, 2021
Heat shock proteins are involved in the response to stress including activation of the immune response. Elevated circulating heat shock proteins are associated with spontaneous preterm birth (SPTB).
Johanna M. Huusko   +14 more
doaj   +1 more source

Eukaryotic DNAJ/K Database: A Comprehensive Phylogenomic Analysis Platform for the DNAJ/K Family [PDF]

open access: yesGenomics & Informatics, 2013
Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD).
Kyeongchae Cheong   +5 more
doaj   +1 more source

Heat Shock Factor Is Involved in Regulating the Transcriptional Expression of Two Potential Hsps (AhHsp70 and AhsHsp21) and Its Role in Heat Shock Response of Agasicles hygrophila

open access: yesFrontiers in Physiology, 2020
Heat shock proteins are molecular chaperones that are involved in numerous normal cellular processes and stress responses, and heat shock factors are transcriptional activators of heat shock proteins.
Jisu Jin   +7 more
doaj   +1 more source

Identification of proteins sensitive to thermal stress in human neuroblastoma and glioma cell lines. [PDF]

open access: yesPLoS ONE, 2012
Heat-shock is an acute insult to the mammalian proteome. The sudden elevation in temperature has far-reaching effects on protein metabolism, leads to a rapid inhibition of most protein synthesis, and the induction of protein chaperones.
Guilian Xu   +6 more
doaj   +1 more source

The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review

open access: yesCells, 2021
Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses.
Ariadni Androvitsanea   +3 more
doaj   +1 more source

Regulation and physiological function of proteins for heat tolerance in cowpea (Vigna unguiculata) genotypes under controlled and field conditions

open access: yesFrontiers in Plant Science, 2022
The expression of heat shock proteins is considered a central adaptive mechanism to heat stress. This study investigated the expression of heat shock proteins (HSPs) and other stress-protective proteins against heat stress in cowpea genotypes under field
Tonny I. Selinga   +10 more
doaj   +1 more source

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