Results 1 to 10 of about 356,638 (158)
Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]
Thrombosis Journal, 2007 Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann Matthias +3 more
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Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor [PDF]
Frontiers in Microbiology, 2022 Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of heat shock sigma factors and activation of genes normally repressed ...
Yehong Huang +12 more
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Diversification of the Caenorhabditis heat shock response by Helitron transposable elements [PDF]
eLife, 2019 Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Jacob M Garrigues +3 more
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Regulation of the mammalian heat shock factor 1 [PDF]
The FEBS Journal, 2017 Living organisms are endowed with the capability to tackle various forms of cellular stress due to the presence of molecular chaperone machinery complexes that are ubiquitous throughout the cell. During conditions of proteotoxic stress, the transcription
Dayalan Naidu, Sharadha +1 more
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Molecular Mechanisms of Heat Shock Factors in Cancer
Cells, 2020 Malignant transformation is accompanied by alterations in the key cellular pathways that regulate development, metabolism, proliferation and motility as well as stress resilience. The members of the transcription factor family, called heat shock factors (
Mikael Christer Puustinen, Lea Sistonen
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Effect of heat shock transcription factor 5(Hsf5) knockdown on heat shock family in mouse Leydig cells and Sertoli cells [PDF]
Jichu yixue yu linchuang, 2023 Objective To investigate the effect of knockdown heat shock transcription factor 5(Hsf5) on the expression of heat shock family in mouse Leydig cells (TM3) and Sertoli cells(TM4).
ZHONG Lin, ZHONG Hongli, DAI Yujie, ZHANG Qinghua
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Heat shock transcription factor HSFB2b negatively regulates plant thermomorphogenesis in Arabidopsis
浙江大学学报. 农业与生命科学版, 2023 In order to explore whether heat shock transcription factor (HSF) known to be involved in plant adaptation to extreme heat stress is also involved in plant thermomorphogenesis at warm temperatures, the result of CRISPR/Cas9 gene editing, physiological ...
YAO Ziwei +3 more
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Functional diversification of heat shock factors
Biologia Futura, 2022 AbstractHeat shock transcription factors (HSFs) are widely known as master regulators of the heat shock response. In invertebrates, a single heat shock factor, HSF1, is responsible for the maintenance of protein homeostasis. In vertebrates, seven members of the HSF family have been identified, namely HSF1, HSF2, HSF3, HSF4, HSF5, HSFX, and HSFY, of ...
Dániel Kovács +3 more
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Is there a role for HSF1 in viral infections?
FEBS Open Bio, 2022 Cells undergo numerous processes to adapt to new challenging conditions and stressors. Heat stress is regulated by a family of heat shock factors (HSFs) that initiate a heat shock response by upregulating the expression of heat shock proteins (HSPs ...
Antonia Reyes +4 more
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Experimental Study on the Evolution of Granite Permeability Under Thermal Shock
Taiyuan Ligong Daxue xuebao, 2021 In order to reveal the change law of permeability of high-temperature granite under thermal shock, the permeability of granite specimens at different temperatures was investigated under four cooling conditions: natural cooling in air and thermal shock ...
Zepeng CHENG +4 more
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