Results 21 to 30 of about 6,066,735 (160)

Transient intracellular acidification regulates the core transcriptional heat shock response

eLife, 2020
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou, Christopher D Katanski, Aaron R Dinner, D Allan Drummond   +3 more
doaj   +1 more source

Immunolocalization of anti-hsf1 to the acetabular glands of infectious schistosomes suggests a non-transcriptional function for this transcriptional activator. [PDF]

PLoS Neglected Tropical Diseases, 2014
Schistosomiasis is a chronically debilitating disease caused by parasitic worms of the genus Schistosoma, and it is a global problem affecting over 240 million people.
Kenji Ishida, Melissa Varrecchia, Giselle M Knudsen, Emmitt R Jolly   +3 more
doaj   +1 more source

The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. [PDF]

PLoS ONE, 2013
The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regulated by the transcription factor HSF1, which is activated upon heat shock and other stresses to induce the
Rachel Raynes, Kathleen M Pombier, Kevin Nguyen, Jessica Brunquell, Jamie E Mendez, Sandy D Westerheide   +5 more
doaj   +1 more source

Regulatory Mechanisms of Heat Stress Response and Thermomorphogenesis in Plants

Plants, 2022
As worldwide warming intensifies, the average temperature of the earth continues to increase. Temperature is a key factor for the growth and development of all organisms and governs the distribution and seasonal behavior of plants. High temperatures lead
Yunzhuan Zhou, Fuxiang Xu, Yanan Shao, Junna He   +3 more
doaj   +1 more source

Temperature, heat shock proteins and growth regulation of the bone tissue

Regulatory Mechanisms in Biosystems, 2022
Ambient heat modulates the elongation of bones in mammals, and the mechanism of such a plasticity has not been studied completely. The influence of heat on growth and development of bone depends on its values.
V. V. Kuibida, P. P. Kohanets, V. V. Lopatynska   +2 more
doaj   +1 more source

Arabidopsis HEAT SHOCK TRANSCRIPTION FACTORA1b overexpression enhances water productivity, resistance to drought, and infection [PDF]

, 2013
Heat-stressed crops suffer dehydration, depressed growth, and a consequent decline in water productivity, which is the yield of harvestable product as a function of lifetime water consumption and is a trait associated with plant growth and development ...
Schöffl, F., Hickman, Richard D. G., Sparrow, Penelope A.C., Albihlal, Waleed S, Lawson, Tracy, Sparrow, P.A.C., Persad, R., Beynon, Jim L., Sparrow, Penelope A. C., Persad, Ramona, Bowden, L., Ott, S., Beynon, Jim L, Hickman, Richard, Bechtold, Ulrike, Beynon, Jim, Baker, Neil R, Mullineaux, Philip M., Schoeffl, Friedrich, Bechtold, U., Schoffl, Friedrich, Baker, N. R., Morison, J.L., Richard, F., Bowden, Laura, Mullineaux, Philip M, Mullineaux, P.M., Martin, Cathie, Albihlal, W.S., Fryer, Michael J., Buchanan-Wollaston, V., Fryer, Michael J, Morison, James I.L., Buchanan-Wollaston, Vicky, Sparrow, Penelope AC, Baker, N.R., Baker, Neil R., Hickman, R., Martin, C., Albihlal, Waleed S., Morison, James I. L., Richard, François, Ott, Sascha, Morison, James IL, Fryer, M.J., Lawson, T., Beynon, J.L.   +46 more
core   +1 more source

Heat shock proteins in tendinopathy: novel molecular regulators [PDF]

, 2012
Tendon disorders-tendinopathies-are the primary reason for musculoskeletal consultation in primary care and account for up to 30% of rheumatological consultations.
Neal L. Millar, George A. C. Murrell, Millar, N.L., Murrell, G.A.C.   +3 more
core   +1 more source

A DNA sequence directed mutual transcription regulation of HSF1 and NFIX involves novel heat sensitive protein interactions. [PDF]

PLoS ONE, 2009
BACKGROUND: Though the Nuclear factor 1 family member NFIX has been strongly implicated in PDGFB-induced glioblastoma, its molecular mechanisms of action remain unknown.
Umashankar Singh, Erik Bongcam-Rudloff, Bengt Westermark   +2 more
doaj   +1 more source

Functional Characterization of the Small Heat Shock Protein Hsp12p from Candida albicans [PDF]

, 2012
Hsp12p is considered to be a small heat shock protein and conserved among fungal species. To investigate the expression of this heat shock protein in the fungal pathogen Candida albicans we developed an anti-CaHsp12p antibody.
Mühlschlegel, Fritz A., Fritz A. Mühlschlegel, De Sordi Luisa, Luisa De Sordi (146209), Fritz A. Mühlschlegel (146212), Fu Man-Shun, De Sordi, L, Fu, Man Shun, Fu, MS, Fritz A Mühlschlegel, Man-Shun Fu, Luisa De Sordi, Mühlschlegel Fritz A., De Sordi, Luisa, Mühlschlegel, FA, Luisa De Sordi¤b, Man-Shun Fu (146203)   +16 more
core   +1 more source

Heat shock induces rapid resorption of primary cilia [PDF]

, 2012
Primary cilia are involved in important developmental and disease pathways, such as the regulation of neurogenesis and tumorigenesis. They function as sensory antennae and are essential in the regulation of key extracellular signalling systems.
Ashworth, R, Prodromou, NV, Osborn, DP, Chapple, JP, Beales, PL, Knight, MM, Thompson, CL, Cogger, KF   +7 more
core   +1 more source