Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]
Thrombosis Journal, 2007 Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann Matthias +3 more
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The Emerging Role of Heat Shock Factor 1 (HSF1) and Heat Shock Proteins (HSPs) in Ferroptosis [PDF]
Pathophysiology, 2023 Cells employ a well-preserved physiological stress response mechanism, termed the heat shock response, to activate a certain type of molecular chaperone called heat shock proteins (HSPs).
Iman Aolymat +2 more
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Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response [PDF]
Cell Reports, 2023 Summary: Despite its pivotal roles in biology, how the transcriptional activity of c-MYC is tuned quantitatively remains poorly defined. Here, we show that heat shock factor 1 (HSF1), the master transcriptional regulator of the heat shock response, acts ...
Meng Xu +8 more
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Robust Heat Shock Response in Chlamydia Lacking a Typical Heat Shock Sigma Factor
Frontiers in Microbiology, 2022 Cells reprogram their transcriptome in response to stress, such as heat shock. In free-living bacteria, the transcriptomic reprogramming is mediated by increased DNA-binding activity of heat shock sigma factors and activation of genes normally repressed ...
Yehong Huang +12 more
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Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study [PDF]
, 2005 BACKGROUND AND PURPOSE: Previous work has shown that soluble heat shock protein 60 (HSP60; sHSP60), present in circulating blood, is associated with carotid atherosclerosis.
XIAO, Q +8 more
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Heat shock transcription factor HSFB2b negatively regulates plant thermomorphogenesis in Arabidopsis
浙江大学学报. 农业与生命科学版, 2023 In order to explore whether heat shock transcription factor (HSF) known to be involved in plant adaptation to extreme heat stress is also involved in plant thermomorphogenesis at warm temperatures, the result of CRISPR/Cas9 gene editing, physiological ...
YAO Ziwei +3 more
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Effect of heat shock transcription factor 5(Hsf5) knockdown on heat shock family in mouse Leydig cells and Sertoli cells [PDF]
Jichu yixue yu linchuang, 2023 Objective To investigate the effect of knockdown heat shock transcription factor 5(Hsf5) on the expression of heat shock family in mouse Leydig cells (TM3) and Sertoli cells(TM4).
ZHONG Lin, ZHONG Hongli, DAI Yujie, ZHANG Qinghua
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Experimental Study on the Evolution of Granite Permeability Under Thermal Shock
Taiyuan Ligong Daxue xuebao, 2021 In order to reveal the change law of permeability of high-temperature granite under thermal shock, the permeability of granite specimens at different temperatures was investigated under four cooling conditions: natural cooling in air and thermal shock ...
Zepeng CHENG +4 more
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Is there a role for HSF1 in viral infections?
FEBS Open Bio, 2022 Cells undergo numerous processes to adapt to new challenging conditions and stressors. Heat stress is regulated by a family of heat shock factors (HSFs) that initiate a heat shock response by upregulating the expression of heat shock proteins (HSPs ...
Antonia Reyes +4 more
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Heat-Induced Conformational Transition Mechanism of Heat Shock Factor 1 Investigated by Tryptophan Probe. [PDF]
Biochemistry, 2022 A transcriptional regulatory system called heat shock response (HSR) has been developed in eukaryotic cells to maintain proteome homeostasis under various stresses.
Kawagoe S +5 more
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