Results 31 to 40 of about 202,314 (262)

Transcriptome analysis of Clematis lanuginosa: Novel features of the molecular events occurring under heat-shock stress

open access: yesOrnamental Plant Research, 2022
The weak heat tolerance of Clematis ornamental varieties negatively affects their ornamental qualities in the summer. To elucidate heat resistance mechanisms, Clematis lanuginosa, which is an important original parent of the Clematis large-flowered group
Linfang Li   +9 more
doaj   +1 more source

A combined modelling and experimental study of heat shock factor SUMOylation in response to heat shock

open access: yesJournal of Theoretical Biology, 2021
One of the most important questions in cell biology is how cell fate is determined when exposed to extreme stresses such as heat shock. It has been long understood that organisms exposed to high temperature stresses typically protect themselves with a heat shock response (HSR), where accumulation of denatured or unfolded proteins triggers the synthesis
Zhang, M., Zhao, A., Guo, C., Guo, L.
openaire   +3 more sources

Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line

open access: yesJournal of Inflammation, 2011
Poly (ADP-ribose) polymerase-1 (PARP-1) is a highly conserved multifunctional enzyme, and its catalytic activity is stimulated by DNA breaks. The activation of PARP-1 and subsequent depletion of nicotinamide adenine dinucleotide (NAD+) and adenosine ...
Zingarelli Basilia   +4 more
doaj   +1 more source

Complex Modes of Heat Shock Factor Activation [PDF]

open access: yesMolecular and Cellular Biology, 1990
Eucaryotic organisms respond to elevated environmental temperatures by rapidly activating the expression of heat shock genes. The transcriptional activation of heat shock genes is mediated by a conserved upstream regulatory sequence, the heat shock element (HSE).
V, Zimarino, C, Tsai, C, Wu
openaire   +2 more sources

Hspb1 inhibits microglial ferroptosis and pro-inflammatory activation to alleviate cerebral ischemia/reperfusion injury in mice

open access: yesNeural Regeneration Research
Heat shock protein beta-1 may be involved in regulating ferroptosis in cells. The expression of heat shock protein beta-1 is upregulated after stroke; however, the underlying mechanism of action of heat shock protein beta-1 in cerebral ischemia ...
Weilong Hua   +10 more
doaj   +1 more source

Hyperthermia increases HSP production in human PDMCs by stimulating ROS formation, p38 MAPK and Akt signaling, and increasing HSF1 activity

open access: yesStem Cell Research & Therapy, 2022
Background Human placenta-derived multipotent cells (hPDMCs) are isolated from a source uncomplicated by ethical issues and are ideal for therapeutic applications because of their capacity for multilineage differentiation and proven immunosuppressive ...
Ju-Fang Liu   +3 more
doaj   +1 more source

Association of heat shock proteins, heat shock factors and male infertility

open access: yesAsian Pacific Journal of Reproduction, 2012
It has been well established that heat shock proteins (HSP) and heat shock factors (HSF) are involved in wide varieties of physiological regulation process and signal pathway. Numerous members of heat shock family exhibit a cell-type-specific expression pattern during spermatogenesis and play crucial roles in germ cell development.
Zi-Liang Ji   +5 more
openaire   +1 more source

Differential gene expression studies on HsfA4d, HsfB2a and ClpD1/HSP100 during heat stress in the rice varieties N22 and Co51

open access: yesElectronic Journal of Plant Breeding, 2020
In the present investigation, differential expression of two transcription factor genes (HsfA4d and HsfB2a) and a heat shock protein (ClpD1/HSP100) was evaluated in the rice varieties N22 and Co 51 using qRT-PCR.
Rishima Maheendran, V. Soundarrajan, N. M. Manikanda Boopathi, R. Gnanam, V. Geethalakshmi and P. Meenakshisundaram
doaj   +1 more source

Absence of ataxin-3 leads to enhanced stress response in C. elegans. [PDF]

open access: yesPLoS ONE, 2011
Ataxin-3, the protein involved in Machado-Joseph disease, is able to bind ubiquitylated substrates and act as a deubiquitylating enzyme in vitro, and it has been involved in the modulation of protein degradation by the ubiquitin-proteasome pathway.
Ana João Rodrigues   +6 more
doaj   +1 more source

Differential recognition of heat shock elements by members of the heat shock transcription factor family [PDF]

open access: yesThe FEBS Journal, 2009
Heat shock transcription factor (HSF), an evolutionarily conserved stress response regulator, forms trimers and binds to heat shock element (HSE), comprising at least three continuous inverted repeats of the sequence 5′‐nGAAn‐3′. The single HSF of yeast is also able to bind discontinuously arranged nGAAn units.
Noritaka, Yamamoto   +4 more
openaire   +2 more sources

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