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BMC Plant Biology, 2020 Background Elevated temperature as a result of global climate warming, either in form of sudden heatwave (heat shock) or prolonged warming, has profound effects on the growth and development of plants.
Li Wang +9 more
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Thermodynamics of Heat Shock Response [PDF]
Physical Review Letters, 1999 Production of heat shock proteins are induced when a living cell is exposed to a rise in temperature. The heat shock response of protein DnaK synthesis in E.coli for temperature shifts from temperature T to T plus 7 degrees, respectively to T minus 7 ...
A. Gragarov +19 more
core +6 more sources
Heat shock suppresses the innate immune response of bovine endometrial epithelial cells [PDF]
Reproduction and FertilityWith rising global temperatures, it is imperative to determine the impact of heat stress on the physiology of food-producing animals. Dairy cows are susceptible to uterine diseases that reduce fertility.
Arslan Tariq +5 more
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HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N 6-methyladenosine [PDF]
Nature Communications, 2019 Cells respond to heat shock with transcriptional and translational adaptations but how HSP90 inhibition alters the heat shock proteome is largely unclear.
Weili Miao +5 more
doaj +3 more sources
Roles of heat shock factor 1 beyond the heat shock response
Cellular and Molecular Life Sciences, 2018 Various stress factors leading to protein damage induce the activation of an evolutionarily conserved cell protective mechanism, the heat shock response (HSR), to maintain protein homeostasis in virtually all eukaryotic cells. Heat shock factor 1 (HSF1) plays a central role in the HSR. HSF1 was initially known as a transcription factor that upregulates
János Barna, P. Csermely, T. Vellai
semanticscholar +4 more sources
Evaluation of Plasma Heat Shock Protein Levels in Smokers
Addicta: The Turkish Journal on Addictions, 2022 This study aims to evaluate the effects of smoking on extracellular heat shock protein levels. Heat shock proteins have been associated with numerous diseases.
Muhammet Kızmaz +3 more
doaj +1 more source
Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities
MedComm, 2022 The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect cells from stresses.
Chen Hu +9 more
semanticscholar +1 more source
Shock the heat shock network [PDF]
Journal of Clinical Investigation, 2009 The targeting of tumors is made possible through establishing protein signatures specific for each cancer type. The recent recognition of the higher expression levels of HSP90 and its accumulation in tumor cell mitochondria has made the HSP90 network a feasible target for neutralization.
Cigdem, Atay +2 more
openaire +2 more sources
Heat shock modulates neutrophil motility in zebrafish. [PDF]
PLoS ONE, 2013 Heat shock is a routine method used for inducible gene expression in animal models including zebrafish. Environmental temperature plays an important role in the immune system and infection progression of ectotherms.
Pui-ying Lam +2 more
doaj +1 more source
Transient intracellular acidification regulates the core transcriptional heat shock response
eLife, 2020 Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou +3 more
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