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Heat shock suppresses the innate immune response of bovine endometrial epithelial cells [PDF]
Reproduction and FertilityWith rising global temperatures, it is imperative to determine the impact of heat stress on the physiology of food-producing animals. Dairy cows are susceptible to uterine diseases that reduce fertility.
Arslan Tariq +5 more
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Heat Shock Proteins and Ferroptosis
Frontiers in Cell and Developmental Biology, 2022 Ferroptosis is a new form of regulatory cell death named by Dixon in 2012, which is characterized by the accumulation of lipid peroxides and iron ions. Molecular chaperones are a class of evolutionarily conserved proteins in the cytoplasm. They recognize
Ying Liu +28 more
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Evaluation of Plasma Heat Shock Protein Levels in Smokers
Addicta: The Turkish Journal on Addictions, 2022 This study aims to evaluate the effects of smoking on extracellular heat shock protein levels. Heat shock proteins have been associated with numerous diseases.
Muhammet Kızmaz +3 more
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Heat shock modulates neutrophil motility in zebrafish. [PDF]
PLoS ONE, 2013 Heat shock is a routine method used for inducible gene expression in animal models including zebrafish. Environmental temperature plays an important role in the immune system and infection progression of ectotherms.
Pui-ying Lam +2 more
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Shock the heat shock network [PDF]
Journal of Clinical Investigation, 2009 The targeting of tumors is made possible through establishing protein signatures specific for each cancer type. The recent recognition of the higher expression levels of HSP90 and its accumulation in tumor cell mitochondria has made the HSP90 network a feasible target for neutralization.
Cigdem, Atay +2 more
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Transient intracellular acidification regulates the core transcriptional heat shock response
eLife, 2020 Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou +3 more
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Frontiers in Physiology, 2020 Heat shock proteins are molecular chaperones that are involved in numerous normal cellular processes and stress responses, and heat shock factors are transcriptional activators of heat shock proteins.
Jisu Jin +7 more
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Lack of peroxisomal catalase affects heat shock response in Caenorhabditis elegans
Life Science Alliance, 2023 The authors present a previously unknown crosstalk between peroxisomes and the heat shock response, whereby the peroxisomal catalase is vital for cellular capacity to survive heat stress and undergo heat-induced lifespan extension.
Marina Musa +5 more
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Heat shock in the springtime [PDF]
Cell Stress and Chaperones, 2014 A collaborative workshop dedicated to the discussion of heat shock factors in stress response, development, and disease was held on April 22-24, 2014 at the Université Paris Diderot in Paris, France. Recent years have witnessed an explosion of interest in these highly conserved transcription factors, with biological roles ranging from environmental ...
Morano, Kevin +2 more
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Post-transcriptional regulation of the trypanosome heat shock response by a zinc finger protein. [PDF]
PLoS Pathogens, 2013 In most organisms, the heat-shock response involves increased heat-shock gene transcription. In Kinetoplastid protists, however, virtually all control of gene expression is post-transcriptional.
Dorothea Droll +6 more
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