Results 1 to 10 of about 568,583 (300)

Lack of peroxisomal catalase affects heat shock response in Caenorhabditis elegans [PDF]

open access: yesLife Science Alliance, 2023
The authors present a previously unknown crosstalk between peroxisomes and the heat shock response, whereby the peroxisomal catalase is vital for cellular capacity to survive heat stress and undergo heat-induced lifespan extension.
Marina Musa   +5 more
doaj   +2 more sources

LPS-induced delayed preconditioning is mediated by Hsp90 and involves the heat shock response in mouse kidney. [PDF]

open access: yesPLoS ONE, 2014
We and others demonstrated previously that preconditioning with endotoxin (LPS) protected from a subsequent lethal LPS challenge or from renal ischemia-reperfusion injury (IRI).
Tamás Kaucsár   +10 more
doaj   +5 more sources

Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius [PDF]

open access: yesmBio, 2023
High-temperature stress is critical for all organisms and induces a profound cellular response. For Crenarchaeota, little information is available on how heat shock affects cellular processes and on how this response is regulated.
Rani Baes   +10 more
doaj   +2 more sources

Unveiling the novel regulatory roles of RpoD-family sigma factors in Salmonella Typhimurium heat shock response through systems biology approaches. [PDF]

open access: yesPLoS Genetics
Three RpoD-family sigma factors, RpoD, RpoS, and RpoH, play critical roles in transcriptional regulation in Salmonella enterica serovar Typhimurium under heat shock conditions.
Joon Young Park   +5 more
doaj   +2 more sources

The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. [PDF]

open access: yesPLoS ONE, 2013
The heat shock response, the cellular response to protein damaging stress, is critical in maintaining proteostasis. The heat shock response is regulated by the transcription factor HSF1, which is activated upon heat shock and other stresses to induce the
Rachel Raynes   +5 more
doaj   +1 more source

The Pathophysiological Role of Heat Shock Response in Autoimmunity: A Literature Review

open access: yesCells, 2021
Within the last two decades, there has been increasing evidence that heat-shock proteins can have a differential influence on the immune system. They can either provoke or ameliorate immune responses.
Ariadni Androvitsanea   +3 more
doaj   +1 more source

Transcriptomic time-series analysis of cold- and heat-shock response in psychrotrophic lactic acid bacteria

open access: yesBMC Genomics, 2021
Background Psychrotrophic lactic acid bacteria (LAB) species are the dominant species in the microbiota of cold-stored modified-atmosphere-packaged food products and are the main cause of food spoilage. Despite the importance of psychrotrophic LAB, their
Ilhan Cem Duru   +5 more
doaj   +1 more source

Transient intracellular acidification regulates the core transcriptional heat shock response

open access: yeseLife, 2020
Heat shock induces a conserved transcriptional program regulated by heat shock factor 1 (Hsf1) in eukaryotic cells. Activation of this heat shock response is triggered by heat-induced misfolding of newly synthesized polypeptides, and so has been thought ...
Catherine G Triandafillou   +3 more
doaj   +1 more source

Is there a role for HSF1 in viral infections?

open access: yesFEBS Open Bio, 2022
Cells undergo numerous processes to adapt to new challenging conditions and stressors. Heat stress is regulated by a family of heat shock factors (HSFs) that initiate a heat shock response by upregulating the expression of heat shock proteins (HSPs ...
Antonia Reyes   +4 more
doaj   +1 more source

Deteriorated stress response in stationary-phase yeast: Sir2 and Yap1 are essential for Hsf1 activation by heat shock and oxidative stress, respectively. [PDF]

open access: yesPLoS ONE, 2014
Stationary-phase cultures have been used as an important model of aging, a complex process involving multiple pathways and signaling networks. However, the molecular processes underlying stress response of non-dividing cells are poorly understood ...
Inbal Nussbaum   +4 more
doaj   +1 more source

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