Results 41 to 50 of about 568,583 (300)

Heat shock proteins and the cellular response to osmotic stress [PDF]

open access: yes, 2000
In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Beck, Franz-X.   +3 more
core   +1 more source

Correction: Heat shock response in archaea [PDF]

open access: yesEmerging Topics in Life Sciences, 2018
Emerging Topics in Life Sciences (2018) https://doi.org/10.1042/ETLS20180024 In the Ahead-of-Print version published on 22 November 2018, the titles/captions for [Figures 1][1] and [3][2] were accompanied by the wrong artwork.
Liesbeth, Lemmens   +2 more
openaire   +2 more sources

Heat Shock Response, Heat Shock Transcription Factor and Cell Aging

open access: yesNeurosignals, 1996
A characteristic feature of aging is a progressive impairment in the ability to adapt to environmental challenges. The purpose of this article is to review the evidence of an attenuated response to heat and physiological stresses in a number of mammalian aging model systems, including the human diploid fibroblasts in culture, whole animals and animal ...
Y K, Lee, D, Manalo, A Y, Liu
openaire   +2 more sources

Heat shock induces expression of OSTC/DC2, a novel subunit of oligosaccharyltransferase, in vitro and in vivo

open access: yesKaohsiung Journal of Medical Sciences, 2014
Mammalian oligosaccharyltransferase complex subunit OSTC/DC2 protein has recently been shown to be a new subunit of the oligosaccharyltransferase; however, its physiological role is still unclear.
Chien-Ming Chen   +7 more
doaj   +1 more source

Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin. [PDF]

open access: yesPLoS ONE, 2012
The molecular mechanisms by which polyglutamine (polyQ)-expanded huntingtin (Htt) causes neurodegeneration in Huntington's disease (HD) remain unclear. The malfunction of cellular proteostasis has been suggested as central in HD pathogenesis and also as ...
Sidhartha M Chafekar, Martin L Duennwald
doaj   +1 more source

Polycomb response elements reduce leaky expression of Cas9 under temperature-inducible Hsp70Bb promoter in Drosophila melanogaster

open access: yesG3: Genes, Genomes, Genetics, 2023
Heat-shock-inducible expression of genes through the use of heat-inducible promoters is commonly used in research despite leaky expression of downstream genes of interest without targeted induction (i.e. heat shock).
Natalie Warsinger-Pepe   +3 more
doaj   +1 more source

Heat shock response of Pseudomonas aeruginosa [PDF]

open access: yesJournal of Bacteriology, 1988
The general properties of the heat shock response in Pseudomonas aeruginosa were characterized. The transfer of cells from 30 to 45 degrees C repressed the synthesis of many cellular proteins and led to the enhanced production of 17 proteins. With antibodies raised against the Escherichia coli proteins, two polypeptides of P.
B, Allan   +4 more
openaire   +2 more sources

Transcriptional profiling of Arabidopsis heat shock proteins and transcription factors reveals extensive overlap between heat and non-heat stress response pathways

open access: yesBMC Genomics, 2007
Background The heat shock response of Arabidopsis thaliana is dependent upon a complex regulatory network involving twenty-one known transcription factors and four heat shock protein families. It is known that heat shock proteins (Hsps) and transcription
Weber Andreas P   +2 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Circuit architecture explains functional similarity of bacterial heat shock responses

open access: yes, 2012
Heat shock response is a stress response to temperature changes and a consecutive increase in amounts of unfolded proteins. To restore homeostasis, cells upregulate chaperones facilitating protein folding by means of transcription factors (TF).
Ala Trusina   +7 more
core   +1 more source

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