Results 31 to 40 of about 271,781 (218)

Heat shock protein 90 has roles in intracellular calcium homeostasis, protein tyrosine phosphorylation regulation, and progesterone-responsive sperm function in human sperm. [PDF]

PLoS ONE, 2014
Heat shock protein 90 plays critical roles in client protein maturation, signal transduction, protein folding and degradation, and morphological evolution; however, its function in human sperm is not fully understood.
Kun Li, Yamei Xue, Aijun Chen, Youfang Jiang, Haifeng Xie, Qixian Shi, Songying Zhang, Ya Ni   +7 more
doaj   +1 more source

Heat Shock Related Protein Expression in Abdominal Testes of Asian Elephant (Elephas maximus)

Animals
The abdominal testes of Asian elephants show normal spermatogenesis. Heat shock in cryptorchid testes elevates heat shock factor (HSF) expression, leading to germ cell apoptosis, while increased heat shock proteins (HSPs) levels provide protection.
Yoko Sato, Theerawat Tharasanit, Chatchote Thitaram, Chaleamchat Somgird, Sittidet Mahasawangkul, Nikorn Thongtip, Kaywalee Chatdarong, Narong Tiptanavattana, Masayasu Taniguchi, Takeshige Otoi, Mongkol Techakumphu   +10 more
doaj   +1 more source

Transcriptome analysis of heat resistance regulated by quorum sensing system in Glaesserella parasuis

Frontiers in Microbiology, 2022
The ability of bacteria to resist heat shock allows them to adapt to different environments. In addition, heat shock resistance is known for their virulence.
Bingzhou Zhang, Bingzhou Zhang, Changsheng Jiang, Changsheng Jiang, Hua Cao, Hua Cao, Wei Zeng, Wei Zeng, Jingping Ren, Jingping Ren, Yaofang Hu, Yaofang Hu, Wentao Li, Wentao Li, Wentao Li, Qigai He, Qigai He   +16 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Heat shock drives genomic instability and phenotypic variations in yeast

AMB Express, 2020
High temperature causes ubiquitous environmental stress to microorganisms, but studies have not fully explained whether and to what extent heat shock would affect genome stability.
Li Shen, Yu-Ting Wang, Xing-Xing Tang, Ke Zhang, Pin-Mei Wang, Yang Sui, Dao-Qiong Zheng   +6 more
doaj   +1 more source

THE EFFECT OF CHROMIUM PICOLINATE SUPPLEMENTATION ON IMMUNE RESPONSE AND HEAT SHOCK PROTEINS OF LAYING HENS UNDER HEAT STRESS CONDITIONS [PDF]

Egyptian Poultry Science, 2018
The present study aimed to investigate the effects of heat shock programs during the growth period without or with chromium picolinate (CrPic) on productive and physiological performance, blood biochemical traits as well as, immune response, heat shock ...
W. Ezzat, E. A. Abdallah, A. M. Rizk, M. M. M. Ouda, Raga Abd El-karim   +4 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Adverse effects of heat shock in rice (Oryza sativa L.) and approaches to mitigate it for sustainable rice production under the changing climate: A comprehensive review

Heliyon
Heat shock, a transient exposure to high temperatures, is a substantial hazard to rice (Oryza sativa L.) production and sustainability. The objective of this review paper is to summarize the impact of heat shock on rice and explore approaches to mitigate
Mohammad Mobarak Hossain, Sharif Ahmed, Mohammad Saiful Alam, Akbar Hossain   +3 more
doaj   +1 more source

Transcriptomic Adaptation of Legionella pneumophila to Transient Heat Shock

Frontiers in Water, 2022
A natural inhabitant of freshwater microbial ecology, Legionella pneumophila is an opportunistically pathogenic bacteria that has found a niche in hot water distribution systems (HWDS) where it challenges hospitals with the spread of nosocomial infection.
Jeffrey Liang, Sebastien P. Faucher
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source