Results 51 to 60 of about 3,954,936 (346)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

BH3-only protein BIM mediates heat shock-induced apoptosis. [PDF]

PLoS ONE, 2014
Acute heat shock can induce apoptosis through a canonical pathway involving the upstream activation of caspase-2, followed by BID cleavage and stimulation of the intrinsic pathway.
Indra M Mahajan, Miao-Der Chen, Israel Muro, John D Robertson, Casey W Wright, Shawn B Bratton   +5 more
doaj   +1 more source

Heat Shock Proteins and Ferroptosis

Frontiers in Cell and Developmental Biology, 2022
Ferroptosis is a new form of regulatory cell death named by Dixon in 2012, which is characterized by the accumulation of lipid peroxides and iron ions. Molecular chaperones are a class of evolutionarily conserved proteins in the cytoplasm. They recognize
Ying Liu, Ying Liu, Ying Liu, Ying Liu, Lin Zhou, Lin Zhou, Lin Zhou, Lin Zhou, Yunfei Xu, Yunfei Xu, Yunfei Xu, Yunfei Xu, Kexin Li, Kexin Li, Kexin Li, Kexin Li, Yao Zhao, Yao Zhao, Yao Zhao, Yao Zhao, Haoduo Qiao, Haoduo Qiao, Haoduo Qiao, Haoduo Qiao, Qing Xu, Qing Xu, Qing Xu, Qing Xu, Jie Zhao   +28 more
doaj   +1 more source

Effect of thermal shock and ruminal incubation on seed germination in Helianthemum apenninum L. Mill (Cistaceae) [PDF]

, 2002
Effect of thermal shock and ruminal incubation on seed germination in Helianthemum apenninum (L.) Mill. (Cistaceae). Here, we analyse the effect of different treatments on seed germination in Helianthemum apenninum (L.) Mill.
Castro, JL, Robles Cruz, Ana Belén
core   +4 more sources

Dynamic m6A mRNA methylation directs translational control of heat shock response

Nature, 2015
The most abundant mRNA post-transcriptional modification is N6-methyladenosine (m6A), which has broad roles in RNA biology. In mammalian cells, the asymmetric distribution of m6A along mRNAs results in relatively less methylation in the 5′ untranslated ...
Jun Zhou, Ji Wan, Xiangwei Gao, Xingqian Zhang, Shu‐Bing Qian   +4 more
semanticscholar   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Prospective determination of heat shock protein serum levels in Saskatchewan women during pregnancyAJOG Global Reports at a Glance

AJOG Global Reports
BACKGROUND: The stress proteins, heat shock protein 27, heat shock protein 70, and αB-crystallin, have all been detected in human serum under normal and disease conditions.
Lindsey Broberg, MD, Ewa I. Miskiewicz, PhD, Jocelyne Martel, MD, Daniel J. MacPhee, PhD   +3 more
doaj   +1 more source

Electro-hyperthermia in Oncology [PDF]

, 2001
Hyperthermia is a rapidly developing treatment method in oncology. The classical effect is based on well-focused energy absorption targeting the malignant tissue.
Szász, András, Szász, Nóra, Szász, Olivér   +2 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

RNAi based transcriptome suggests genes potentially regulated by HSF1 in the Pacific oyster Crassostrea gigas under thermal stress

BMC Genomics, 2019
Background The Pacific oyster Crassostrea gigas is an important fishery resource that is sensitive to temperature fluctuations. Thus, it has evolved a protection mechanism against heat stress by increasing the expression of the gene coding for heat shock
Youli Liu, Li Li, Baoyu Huang, Wei Wang, Guofan Zhang   +4 more
doaj   +1 more source