Results 81 to 90 of about 23,911 (226)

How Salmonella Works Under Osmotic and Desiccation Stresses

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Salmonella remains one of the leading threats in foods with reduced water activity, where it can survive for long periods and cause outbreaks. Its persistence stems from a wide array of adaptive strategies shaped by the selective pressures imposed by low‐moisture foods.
Mayara Messias Oliveira, Dionisio P. Amorim‐Neto, Anderson S. Sant'Ana   +2 more
wiley   +1 more source

A Study of the Infant Nasal Microbiome Development over the First Year of Life and in Relation to Their Primary Adult Caregivers Using cpn60 Universal Target (UT) as a Phylogenetic Marker. [PDF]

PLoS ONE, 2016
Whereas the infant gut microbiome is the subject of intense study, relatively little is known regarding the nares microbiome in newborns and during early life.
Shelley W Peterson, Natalie C Knox, George R Golding, Shaun D Tyler, Andrea D Tyler, Philip Mabon, Joanne E Embree, Fiona Fleming, Sergio Fanella, Gary Van Domselaar, Michael R Mulvey, Morag R Graham   +11 more
doaj   +1 more source

Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria [PDF]

, 1989
A nuclear encoded mitochondrial heat-shock protein hsp60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix.
Cheng, Ming Yuan, Hallberg, Elisabeth M., Hallberg, Richard L., Hartl, Franz-Ulrich, Horwich, Arthur, Kalousek, Frantisek, Martin, Jörg, Neupert, Walter, Pollock, Robert A.   +8 more
core   +1 more source

Targeting ParPMC Susceptibility Hubs in Prunus: eEF1A as a Conserved Mediator of Plum Pox Virus Infection in Nicotiana benthamiana

Molecular Plant Pathology, Volume 27, Issue 5, May 2026.
ParPMC interactors were screened, highlighting eEF1A proteins; co‐localization and VIGS show their role in PPV infection and sharka susceptibility. ABSTRACT Sharka, caused by Potyvirus plumpoxi (plum pox virus, PPV), is the most destructive viral disease affecting Prunus species worldwide.
Ángela Polo‐Oltra, Alba Lloret, Jesús A. Sánchez‐Navarro, Gabino Ríos, Carlos Romero, Elena Zuriaga   +5 more
wiley   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Gardnerella vaginalis Subgroups Defined by cpn60 Sequencing and Sialidase Activity in Isolates from Canada, Belgium and Kenya. [PDF]

PLoS ONE, 2016
Increased abundance of Gardnerella vaginalis and sialidase activity in vaginal fluid is associated with bacterial vaginosis (BV), a common but poorly understood clinical entity associated with poor reproductive health outcomes.
John J Schellenberg, Teenus Paramel Jayaprakash, Niradha Withana Gamage, Mo H Patterson, Mario Vaneechoutte, Janet E Hill   +5 more
doaj   +1 more source

Transcriptome profiling of grapevine seedless segregants during berry development reveals candidate genes associated with berry weight [PDF]

, 2016
Indexación: Web of Science; PubMedBackground Berry size is considered as one of the main selection criteria in table grape breeding programs. However, this is a quantitative and polygenic trait, and its genetic determination is still poorly understood ...
A Doligez, A Roberts, A Zamboni, AJ Bais, Alejandro Maass, Alex Di Genova, AM Almeida, AP Friend, Ariel Orellana, AS Negri, BG Coombe, BG Coombe, BG Coombe, BM Fischer, C Chen, C Conde, C Houel, C Pastore, C Pratt, C Sweetman, C Trapnell, CA Ledbetter, Claudia Muñoz-Espinoza, D Costenaro da Silva, D Lijavetzki, D Moreno, D Schenck, DH Lorenz, F Carrari, F Dyda, FG Silva da, FJ Pérez, G Fanizza, GR Cramer, I Debeaujon, J Correa, J Correa, J Guo, J Tello, J Xu, JA Cabezas, José Correa, JP Nitsch, K Chen, K Yang, KCH Amrine, L Bogrë, L Costantini, L Deluc, L Fernandez, M Barticevic, M Chakrabarti, M Fasoli, M González-Agüero, M Lu, M Rienth, M Salmaso, Mauricio González-Agüero, MB Ali, MC Palumbo, MJ Carmona, MJ Martínez-Esteso, MK Aradhya, N Mejía, N Mejía, N Schumann, N Wang, N Yokotani, NS Watson-Haigh, O Gudenschwager, O Jaillon, P Barba, P Langcake, P Neudecker, P Nicolas, Patricio Hinrichsen, R Core Team, R Ursem, Romina Silva, S Dal Santo, S Epskamp, S Guillaumie, S Lê, S Myles, S Taylor, S Zenoni, SBP Athauda, T Sekito, T Wei, X Chen, Z Du   +90 more
core   +3 more sources

Clostridioides difficile‐Derived Extracellular Vesicles Induce Proinflammatory Responses in Macrophages

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT Clostridioides difficile (CD) is a leading cause of antibiotic‐associated diarrhoea in both hospitalized and non‐hospitalized patients. This study explores the role of extracellular vesicles (EVs) derived from Clostridioides difficile strain 630 (CD630‐EVs), which released spherical EVs during in vitro culture, in modulating pro‐inflammatory ...
Fangfang Fan, Yu Zeng, Qianli Zhao, Tongxuan Su, Yining Shen, Wei Chen, Cen Jiang, Qi Ni, Yiyue Liu, Ru Fan, Danfeng Dong, Yibing Peng   +11 more
wiley   +1 more source

In vitro dissociation and self‐assembly of three chaperonin 60s: the role of ATP [PDF]

FEBS Letters, 1995
A comparative study has investigated the in vitro dissociation and self‐assembly of chaperonin 60 14‐mers isolated from E. coli (GroEL), yeast mitochondria and pea chloroplasts. In all cases Mg2+ inhibits, and low temperature stimulates, the urea‐induced dissociation. ATP or ADP in the presence of Mg2+ enhance the dissociation of the chaperonins.
openaire   +2 more sources

Effects of confinement and crowding on folding of model proteins

, 2008
We perform molecular dynamics simulations for a simple coarse-grained model of crambin placed inside of a softly repulsive sphere of radius R. The confinement makes folding at the optimal temperature slower and affects the folding scenarios, but both ...
Baruah, Baukmketner, Cheung, Cieplak, Cieplak, Cieplak, Duroux, Ellis, Go, Hartl, Hoang, Honeycutt, Jewett, Kwiecinska, Luisi, M. Wojciechowski, Marek Cieplak, Matzke, Melo, Moilanen, Murtas, Rathore, Sulkowska, Sulkowska, Szymczak, Szymczak, Takagi   +26 more
core   +1 more source