Results 31 to 40 of about 3,064 (126)

Investigations on the microbial catabolism of the organic sulfur compounds TDP and DTDP in H16 employing DNA microarrays [PDF]

open access: yes, 2010
In this study, we have investigated the transcriptome of Ralstonia eutropha H16 during cultivation with gluconate in presence of 3,3'-thiodipropionic acid (TDP) or 3,3'-dithiodipropionic acid (DTDP) during biosynthesis of poly(3-hydroxybutyrate-co-3 ...
Alexander Steinbüchel   +4 more
core   +2 more sources

Transcriptome profiling of megakaryocytes and platelets: Application to GP9‐ and IKZF5‐related thrombocytopenia

open access: yesHemaSphere, Volume 9, Issue 9, September 2025.
Abstract Platelets are anucleate cells produced in the bone marrow and derived from large progenitor cells called megakaryocytes (MKs). Platelets receive RNA transcripts from their progenitorial MKs during thrombopoiesis. However, the correspondence between platelet and MK transcriptomes is poorly understood, particularly in the context of germline ...
Koenraad De Wispelaere   +7 more
wiley   +1 more source

Quorum Sensing via Autoinducer‐2 Promotes Colonisation and Host Adaptation in B. bifidum PRL2010

open access: yesMicrobial Biotechnology, Volume 18, Issue 9, September 2025.
Autoinducer‐2 (AI‐2), encoded by the luxS gene, is a molecule involved in the quorum sensing mechanism in bifidobacteria, typical intestinal bacteria. In this manuscript, the distribution of this gene in all bifidobacterial genomes deposited in the database has been studied.
Francesca Turroni   +11 more
wiley   +1 more source

Bioinformatic analyses in early host response to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) reveals pathway differences between pigs with alternate genotypes for a major host response QTL [PDF]

open access: yes, 2016
GO term enrichment performed on all 10 dpi time by time comparisons. For every time by time comparison the Enrichment Score for the significant DAVID clusters as well as a description of these clusters is presented for up-regulated and down-regulated ...
Arun Kommadath   +14 more
core   +5 more sources

Personalized Medicine in Ocular Fibrosis: Myth or Future Biomarkers [PDF]

open access: yes, 2016
SIGNIFICANCE: Fibrosis-related events play a part in the pathogenesis or failure of treatment of virtually all the blinding diseases around the world, and also account for over 40% of all deaths.
Khaw, PT, Yu-Wai-Man, C
core   +1 more source

Exploring the human archaeome: its relevance for health and disease, and its complex interplay with the human immune system

open access: yesThe FEBS Journal, Volume 292, Issue 6, Page 1316-1329, March 2025.
This work investigates the archaeome, an essential segment of the human microbiome, focusing on its relationship with the immune system. Here, we outline the types of archaea across different body areas and underscore possible links to health issues, such as obesity and specific cancers.
Torben Kuehnast   +5 more
wiley   +1 more source

14‐3‐3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer

open access: yesInternational Journal of Cancer, Volume 156, Issue 3, Page 623-637, 1 February 2025.
What's new? 14‐3‐3σ functions as an oncogene in colorectal cancer and is associated with therapy resistance. However, the underlying mechanisms remain unclear. Here, the authors show that 14‐3‐3σ restricts the localization of the transcription factor YY1 to the cytoplasm, preventing it from repressing genes of the unfolded protein response pathway ...
Amol Lonare   +8 more
wiley   +1 more source

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]

open access: yes, 2018
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...
Abdel-Rahman, Mohamed H.   +784 more
core   +2 more sources

Multiple Chaperone DnaK–FliC Flagellin Interactions are Required for Pseudomonas aeruginosa Flagellum Assembly and Indicate a New Function for DnaK

open access: yesMicrobial Biotechnology, Volume 18, Issue 2, February 2025.
The dogma on the heat shock DnaK chaperone establishes its fundamental cytosolic role in folding and unfolding intracellular proteins. This study reveals its tight association with the flagellin, its secretion, likely through the flagellum apparatus, its insertion into a growing flagellum filament and a novel extracellular ATP‐independent chaperone ...
Gabriella Molinari   +17 more
wiley   +1 more source

Joint Analysis of Multiple Omics to Describe the Biological Characteristics of Resistant Hypertension

open access: yesThe Journal of Clinical Hypertension, Volume 27, Issue 1, January 2025.
Abstract Resistant hypertension (RH) may cause severe target organ damage and poses significant challenges in the field of hypertension prevention and treatment. Mining biological characteristics is crucial for exploring the pathogenesis of RH and for early diagnosis and treatment.
Shanshan Wang   +8 more
wiley   +1 more source

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