Results 91 to 100 of about 387,776 (314)

Stabilizing effect of delay distribution for a class of second-order systems without instantaneous feedback

open access: yes, 2009
In many situations in physics, engineering and biology time delays arise naturally due to the time needed to transport information from one part of the system to another and/or to react to incoming information. When differential equations are used in the
Gabor Kiss   +3 more
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A Necessary Characteristic Equation of Diffusion Processes Having Gaussian Marginals

open access: yes, 2020
The aim of this work is to characterize one-dimensional homogeneous diffusion process, under the assumption that marginal density of the process is Gaussian.
Syeda Rabab Mudakkar
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Delay differential equation models for real-time dynamic substructuring

open access: yes, 2005
Real-time dynamic substructuring is a testing technique that models an entire system through the combination of an experimental test piece, representing part of the system, with a numerical model of the rest of the system.
Wagg, DJ   +4 more
core  

MEASUREMENT THEORY OF THE CAVITY CHARACTERISTIC EQUATION METHOD AND EXPERIMENTAL RESEARCH ON MICROWAVE PERMEABILITY FOR FERRITES

open access: yes, 1991
The characteristic equation for a TE102 or TE104 rectangular cavity loaded by a ferrite slab in the middle has been derived on the basis of electromagnetic theory.
Jin Liu   +9 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

STUDY OF THIRD-ORDER SYSTEM STABILITY IN THE SPACE OF CHARACTERISTIC EQUATION COEFFICIENTS

open access: yes, 2016
The problem of building the stability space for third-order control system is solved. The 3D stability space has coefficients of characteristic equation as coordinates. Analytical conditions of system stability are defined. Different variants of crossing
A. B. Prokofev, S. V. Safonov
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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