Results 111 to 120 of about 387,776 (314)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
CHARACTERISTIC PROBLEM FOR THE LOADED WAVE EQUATION WITH SPECIFIC CHANGES
, 2015 In this paper the characteristic problem for the wave equation loaded with a special shift. A theorem on the uniqueness of the solution of the Goursat problem and find necessary conditions for its ...
A.Kh. Attaev
core +1 more source
Recirculating Flows Involving Short Fiber Suspensions: Numerical Difficulties and Efficient Advanced Micro-Macro Solvers [PDF]
, 2009 Numerical modelling of non-Newtonian flows usually involves the coupling between equations of motion characterized by an elliptic character, and the fluid constitutive equation, which defines an advection problem linked to the fluid history.
CHINESTA SORIA, Francisco +4 more
core +1 more source
Conservation Equations and Characteristics
, 2016 A conservation law for a physical system states that a certain quantity (e.g., mass, energy, or momentum) is independent of time. For continuous systems such as fluids or gases, these global quantities can be defined as integrals of density functions. The conservation law then translates into a local form, as a PDE for the density function.
openaire +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
This study reports a didactic approach on how to exploit the knowledge of the characteristic equations of any second-order system towards their stability analysis.
M. N. Kamarudin +4 more
core +1 more source
THE CHARACTERISTIC EQUATION FOR THE DETERMINATION OF THE VIBRATION INHERENT FREQUENCIES AT BENDING FROM TWO-SHAFTS TRANSMISSION [PDF]
Fiabilitate şi Durabilitate, 2018 To avoid system resonance operation is necessary to know the most accurate values its pulsations and taking appropriate constructive measures to avoid overlapping with disturbing frequency harmonics n,2n,3n (n the transmission speed).
Ion BULAC
doaj
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Ince-Gaussian laser beams as superposition of Hermite-Gaussian or Laguerre-Gaussian beams
Компьютерная оптикаWe obtain explicit analytic expressions for the Ince-Gaussian (IG) beams for several first indices p = 3, 4, 5, 6. Earlier, explicit expressions have been derived for amplitudes of the IG beams with p = 0, 1, 2 and without regard for the ellipticity ...
E.G. Abramochkin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source