Results 111 to 120 of about 2,364,233 (302)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Unusual effects of anisotropy on the specific heat of ceramic and single crystal MgB2

, 2002
The two-gap structure in the superconducting state of MgB_2 gives rise to unusual thermodynamic properties which depart markedly from the isotropic single-band BCS model, both in their temperature- and field dependence. We report and discuss measurements
A. Junod, An, Angst, Bachmann, Belashchenko, Binnig, Bouquet, Bouquet, Brinkman, Bud’ko, Bud’ko, Caroli, Caroli, Carrington, Choi, Choi, Combescot, Corak, Dhallé, Eisterer, Eskildsen, F. Bouquet, Fisher, Gerashenko, Golubov, Golubov, Golubov, H.W. Weber, Haas, Hinks, I. Sheikin, Ichioka, Junod, Junod, Junod, Kogan, Komori, Kong, Kortus, Kotegawa, Lee, Liu, M. Eisterer, Manzano, Mazin, Mirmelstein, Moler, Moskalenko, Mühlschlegel, Nagamatsu, Nakai, Osborn, P. Toulemonde, Padamsee, Papavassiliou, Patnaik, Posazhennikova, Rosner, S. Lee, S. Tajima, Sanchez, Satta, Shen, Shulga, Sologubenko, Suhl, Sullivan, Volovik, Wang, Wang, Wälti, Y. Wang, Yang, Yoyoka, Zehetmayer   +74 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Real space analysis of inherent structures

, 2004
We study a generalization of the one-dimensional disordered Potts model, which exhibits glassy properties at low temperature. The real space properties of inherent structures visited dynamically are analyzed through a decomposition into domains over ...
Bray A. J., Bray A. J., Crisanti A., Derrida B., E Bertin, Marinari E., Rieger H., Stillinger F. H., Thouless D. J.   +8 more
core   +5 more sources

characteristic temperatures

Citation: 'characteristic temperatures' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12746 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Research on the Temperature Characteristics of 1 200 V 4H-SiC Junction Barrier Schottky Diode

Kongzhi Yu Xinxi Jishu, 2016
In order to research the effect of temperature on static electrical parameters of 4H–SiC junction barrier Schottky (JBS) diode,1.2 kV 4H–SiC JBS diodes were fabricated and their current-voltage characteristics were measured in the range of 25 ℃ ~150 ...
YUAN Hao, SONG Qingwen, TANG Xiaoyan, YUAN Lei, ZHANG Yimen, ZHANG Yuming   +5 more
doaj  

Performance of carbon nanomaterials incorporated with concrete exposed to high temperature

Nanotechnology Reviews
In recent decades, there have been initiatives to incorporate carbon nanomaterials (CNMs) into cement composites, particularly graphene oxide (GO), carbon nanotubes, graphite (GP), and mild carbon (MC).
Han Seungyeon, Hossain Mohammad Shakhawat, Ha Taeho, Yun Kyong Ku   +3 more
doaj   +1 more source

Time scale for the onset of Fickian diffusion in supercooled liquids

, 2005
We propose a quantitative measure of a time scale on which Fickian diffusion sets in for supercooled liquids and use Brownian Dynamics computer simulations to determine the temperature dependence of this onset time in a Lennard-Jones binary mixture.
B. Doliwa, D. Chandler, Elijah Flenner, Grzegorz Szamel, J. P. Hansen   +4 more
core   +1 more source