Results 101 to 110 of about 17,389,636 (280)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Physiological, biochemical and transcriptomic analyses reveal the mechanism of variation in color traits in Panax japonicus fruits

Scientific Reports
Panax japonicus C. A. Mey. is a rare and endangered Class II important protected wild medicinal plant in China with a wide range of pharmacological activities.
Xi Lun Huang, Rui Jin, Ting Ting Tang, E. Liang, Lai Zhang   +4 more
doaj   +1 more source

Mechanistic insights into I₂O₅ heterogeneous hydrolysis and its role in iodine aerosol growth in pristine and polluted atmospheres [PDF]

Atmospheric Chemistry and Physics
Higher-order iodine oxides are intricately linked to marine aerosol formation; however, the underlying physicochemical mechanisms remain poorly constrained, particularly for I2O5, which is stable yet conspicuously absent in the atmosphere.
X. Deng, A. Ning, L. Liu, F. Bai, F. Bai, J. Yang, J. Li, J. Liu, X. Zhang   +8 more
doaj   +1 more source

Characteristics of Sunset radar [PDF]

, 1983
Located in a narrow canyon 15 km west of Boulder, Colorado, the Sunset pulsed Doppler radar was the first radar designed and constructed specifically as a VHF ST radar.
Green, J. L.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Safety Analysis of Aircraft Icing Detection System Based on Fault Tree

Hangkong gongcheng jinzhan, 2018
Aircraft icing detection system is very important to guarantee flight safety. It is also a new problem to assess safety of the aircraft icing detection system.
Wang Xiaohui, Che Cheng, Hu Yang, Hua Ming   +3 more
doaj   +1 more source

Descriptive Analysis of Sexual Assault Nurse Examinations in Bethel: 2005-2006 [PDF]

, 2007
This project examined the characteristics of 105 sexual assault victimizations recorded by sexual assault nurse examiners in Bethel, Alaska in 2005 and 2006.
Henry, Tara, Rosay, André B., The Alaska Department of Law, Yukon-Kuskokwim Health Corporation   +3 more
core  

Characteristics of Real Futures Trading Networks

, 2011
Futures trading is the core of futures business, and it is considered as one of the typical complex systems. To investigate the complexity of futures trading, we employ the analytical method of complex networks.
Albert, Albert, Albert, Barabási, Barabási, Barrat, Barrat, Battiston, Bianconi, Boccaletti, Bonanno, Broder, Calderia, Clauset, da, Dorogovtsev, Faloutsos, Freeman, Fu, Gallos, Garlaschelli, Goh, Guimerà, Han, Huberman, Jeong, Jiang, Jihong Guan, Junjie Wang, Kurant, Leskovec, Li, Liu, Liu, Liu, Mantegna, Motter, Newman, Newman, Newman, Newman, Newman, Newman, Onnela, Onnela, Ou, Pan, Pastor-Satorras, Ravasz, Shuigeng Zhou, Song, Su, Subrahmanyam, Tumminello, Wang, Wang, Watts, Zhang, Zhou, Zhu   +59 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source