Results 111 to 120 of about 5,356,378 (346)
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source
FEBS Letters, EarlyView.Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur +5 more
wiley +1 more source
Isolation and Characterization of Biosynthetic Arylsulphates [PDF]
, 1954 K. S. Dodgson +2 more
openalex +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A Characterization of Normality
The Annals of Mathematical Statistics, 1967 A probability distribution on an $n$-dimensional Euclidean space can be specified by giving either the joint distribution of the usual rectangular coordinates or by the joint distribution of the polar coordinates. The object of this note is to obtain a characterization of normality in terms of independence of these coordinates under suitable regularity
openaire +3 more sources
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
The Monoketo- and Monohydroxyoctadecanoic Acids. Preparation and Characterization by Thermal and X-ray Methods. [PDF]
, 1952 Sune Bergström +4 more
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Journal of Algebra, 1997 This paper, using modern techniques, presents a simplified local characterization of the Mathieu simple group \(M_{22}\). The main result is the following: Let \(G\) be a finite group with an involution \(z\) such that \(H=C_G(z)\) contains a normal extraspecial group \(Q\) of order 32 such that \(Z(Q)=\langle z\rangle\), \(H/Q\cong Z_2\times S_3 ...
openaire +3 more sources
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source