Results 61 to 70 of about 5,356,378 (346)

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

FEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield, Torsten Kleffmann, David J. Saul, Sigurd M. Wilbanks   +3 more
wiley   +1 more source

Unlocking thin sand potential: a data-driven approach to reservoir characterization and pore pressure mapping

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
The gradual decline of production of the major fields of the Indus Basin has influenced the field pressure. Therefore, the prospects need to be assessed by the petro-elastic relationship.
Muhsan Ehsan, Rujun Chen, Umar Manzoor, Muyyassar Hussain, Kamal Abdelrahman, Zahid Ullah Khan, Jar Ullah, Muhammad Khizer Iftikhar, Farooq Arshad   +8 more
doaj   +1 more source

Micro-scale opto-thermo-mechanical actuation in the dry adhesive regime

Light: Science & Applications, 2021
A general principle enabling the actuation of micro-objects on dry frictional surfaces based on opto-thermo-mechanical effects is established and two-dimensional spiral motions of gold plates on micro-fibers are experimentally demonstrated.
Weiwei Tang, Wei Lyu, Jinsheng Lu, Fengjiang Liu, Jiyong Wang, Wei Yan, Min Qiu   +6 more
doaj   +1 more source

A characterization of hypercubes

Discrete Mathematics, 1977
AbstractA combinatorial characterization of hypercubes is given. A hypercube is defined as the undirected Hasse diagram of a Boolean lattice. The method used is inductive extension of partial isomorphisms.
openaire   +2 more sources

Comprehensive genomic characterization of head and neck squamous cell carcinomas

Nature, 2015
The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas (HNSCCs) to provide a comprehensive landscape of somatic genomic alterations.
M. Lawrence, C. Sougnez, Lee T Lichtenstein, K. Cibulskis, E. Lander, S. Gabriel, G. Getz, Adrian Ally, M. Balasundaram, I. Birol, R. Bowlby, Denise Brooks, Y. Butterfield, R. Carlsen, Dean Cheng, Andy Chu, Noreen Dhalla, R. Guin, R. Holt, Steven J. M. Jones, Darlene Lee, H. Li, M. Marra, Michael Mayo, Richard A. Moore, A. Mungall, A. G. Robertson, J. Schein, Payal Sipahimalani, Angela Tam, N. Thiessen, Tina Wong, A. Protopopov, Netty G Santoso, Semin Lee, Michael G Parfenov, Jianhua Zhang, Harshad S. Mahadeshwar, Jiabin Tang, X. Ren, S. Seth, Psalm S. Haseley, Dong Zeng, Lixing Yang, A. W. Xu, Xingzhi Song, A. Pantazi, C. Bristow, Angela Hadjipanayis, J. Seidman, L. Chin, P. Park, R. Kucherlapati, Rehan Akbani, Tod D. Casasent, Wenbin Liu, Yiling Lu, G. Mills, Thomas C. Motter, J. Weinstein, L. Diao, Jing Wang, Youhong Fan, Jinze Liu, Kai Wang, J. Auman, S. Balu, T. Bodenheimer, Elizabeth Buda, D. Hayes, K. Hoadley, A. Hoyle, S. Jefferys, Corbin D. Jones, P. Kimes, Yufeng Liu, J. Marron, S. Meng, P. Mieczkowski, Lisle E. Mose, J. Parker, C. Perou, J. Prins, J. Roach, Yan Shi, J. Simons, Darshan Singh, Matthew G. Soloway, Donghui Tan, Umadevi Veluvolu, Vonn Walter, S. Waring, M. Wilkerson, Junyuan Wu, N. Zhao, A. Cherniack, P. Hammerman, A. Tward, C. Pedamallu, G. Saksena, Joonil Jung, A. Ojesina, S. Carter, Travis Zack, S. Schumacher, R. Beroukhim, S. Freeman, M. Meyerson, Juok Cho, M. Noble, D. Dicara, Hailei Zhang, David I Heiman, Nils Gehlenborg, Douglas Voet, Pei Lin, S. Frazer, P. Stojanov, Yingchun Liu, L. Zou, Jaegil Kim, D. Muzny, H. Doddapaneni, C. Kovar, J. Reid, Donna Morton, Yi Han, Walker Hale, H. Chao, K. Chang, J. Drummond, R. Gibbs, N. Kakkar, D. Wheeler, Liu Xi, G. Ciriello, M. Ladanyi, William Lee, Ricardo Ramirez, C. Sander, R. Shen, Rileen Sinha, Nils Weinhold, B. Taylor, B. A. Aksoy, Gideon Dresdner, Jianjiong Gao, Benjamin E. Gross, A. Jacobsen, B. Reva, N. Schultz, S. O. Sumer, Yichao Sun, T. Chan, L. Morris, Joshua M. Stuart, S. Benz, S. Ng, C. Benz, C. Yau, S. Baylin, L. Cope, Ludmila V. Danilova, J. Herman, Moiz Bootwalla, D. Maglinte, P. Laird, T. Triche, D. Weisenberger, D. V. Berg, N. Agrawal, J. Bishop, P. Boutros, J. Bruce, L. Byers, J. Califano, T. Carey, Zhong Chen, Hui Cheng, Simion I. Chiosea, E. Cohen, B. Diergaarde, A. Egloff, A. El-Naggar, R. Ferris, M. Frederick, J. Grandis, Yanzhu Guo, R. Haddad, Thomas M. Harris, A. Hui, J. Lee, S. Lippman, Fei-Fei Liu, J. Mchugh, J. Myers, P. Ng, B. Perez–Ordoñez, C. Pickering, M. Prystowsky, M. Romkes, Anthony D Saleh, M. Sartor, R. Seethala, T. Seiwert, H. Si, C. Waes, Daryl Waggott, M. Wiznerowicz, W. Yarbrough, Jiexin Zhang, Zhixiang Zuo, K. Burnett, D. Crain, J. Gardner, Kevin R Lau, D. Mallery, S. Morris, J. Paulauskis, R. Penny, C. Shelton, T. Shelton, M. Sherman, P. Yena, Aaron D. Black, Jay Bowen, J. Frick, J. Gastier-Foster, H. Harper, K. Leraas, T. Lichtenberg, N. Ramirez, L. Wise, E. Zmuda, J. Baboud, M. Jensen, A. Kahn, T. Pihl, D. Pot, Deepak Srinivasan, Jessica L Walton, Yunhu Wan, R. Burton, Tanja Davidsen, John A. Demchok, G. Eley, M. Ferguson, K. Shaw, B. Ozenberger, Margi Sheth, H. Sofia, R. Tarnuzzer, Zhining Wang, Liming Yang, J. Zenklusen, Charles Saller, Katherine Tarvin, Chu Chen, R. Bollag, P. Weinberger, W. Golusiński, P. Golusiński, Matthew Ibbs, Konstanty Korski, A. Mackiewicz, W. Suchorska, Bartosz Szybiak, Erin E. Curley, C. Beard, Colleen M. Mitchell, G. Sandusky, Julie Ahn, Zubair Khan, J. Irish, J. Waldron, W. William, Sophie C. Egea, C. Gomez-Fernandez, Lynn M. Herbert, C. Bradford, D. Chepeha, Andrea Haddad, Tamara R. Jones, Christine M. Komarck, Mayya Malakh, J. Moyer, Ariane Nguyen, Lisa A. Peterson, M. Prince, L. Rozek, Evan G. Taylor, H. Walline, G. Wolf, L. Boice, B. Chera, W. Funkhouser, M. Gulley, T. Hackman, M. Hayward, Meijuan Huang, W. Rathmell, Ashley H. Salazar, W. Shockley, C. Shores, L. Thorne, M. Weissler, Sylvia Wrenn, A. Zanation, Brandee T. Brown, M. Pham   +309 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Characterizing Cautious Choice [PDF]

SSRN Electronic Journal, 2005
The set of maximin actions in general decision problems is characterized. Ministerio de Educación y Ciencia. Fondos FEDER | Ref. SEJ2005-07637-C02-02 Xunta de Galicia | Ref.
Mark Voorneveld, Mark Voorneveld, Peter Borm, Manuel A. Mosquera, Ignacio García-Jurado, M. Gloria Fiestras-Janeiro   +5 more
openaire   +11 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Design and Construction of a Brain-Like Computer: A New Class of Frequency-Fractal Computing Using Wireless Communication in a Supramolecular Organic, Inorganic System

Information, 2014
Here, we introduce a new class of computer which does not use any circuit or logic gate. In fact, no program needs to be written: it learns by itself and writes its own program to solve a problem.
Subrata Ghosh, Krishna Aswani, Surabhi Singh, Satyajit Sahu, Daisuke Fujita, Anirban Bandyopadhyay   +5 more
doaj   +1 more source

Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors

npj Precision Oncology, 2022
Molecular profiling of childhood CNS tumors is critical for diagnosis and clinical management, yet tissue access is restricted due to the sensitive tumor location.
Erin R. Bonner, Robin Harrington, Augustine Eze, Miriam Bornhorst, Cassie N. Kline, Heather Gordish-Dressman, Adam Dawood, Biswajit Das, Li Chen, Rini Pauly, P. Mickey Williams, Chris Karlovich, Amanda Peach, D’andra Howell, James Doroshow, Lindsay Kilburn, Roger J. Packer, Sabine Mueller, Javad Nazarian   +18 more
doaj   +1 more source