Atmospheric Pressure Corona Discharge Ionization of <i>n</i>-Heptane (I): Formation of the Molecular Ion M<sup>+•</sup> and Dehydrogenated Ions [M - 2H]<sup>+•</sup> and [M - <i>n</i>H]<sup>+</sup> (<i>n</i> = 1, 3, 5). [PDF]
Fukuyama D +4 more
europepmc +1 more source
GW Approximation Coupled with Classical Fluctuating Charges and Dipoles. [PDF]
Nottoli G +5 more
europepmc +1 more source
Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok +4 more
wiley +2 more sources
Discovery of a Reversible Sub‐Picomolar Thrombin Inhibitor Using DCC
An ultrapotent yet fully reversible trivalent thrombin inhibitor discovered through screening a large dynamic combinatorial library (DCL) of 125 000 members of self‐assembled fragments. The innovative approach leverages size‐exclusion‐based affinity selection, coupled with MALDI‐TOF mass spectrometry readout, enabling the full workflow to be completed ...
Millicent Dockerill +2 more
wiley +2 more sources
Resolving charge and glycosylation variants of cetuximab combining offline ion-exchange and hydrophilic interaction chromatography-HRMS. [PDF]
van der Zon AAM, Gargano AFG.
europepmc +1 more source
Redirecting Excited‐State Proton Transfer Through Supramolecular Polymerization in Nanoconfinement
Supramolecular confinement redirects the excited‐state proton transfer pathway of an amphoteric emitter. In water, the molecule undergoes ESPD, whereas co‐assembly with γ‐cyclodextrin forms nanotubes that template slip‐stacked emitter pairs and enable ESIMPT. Structural and photophysical characterization of the assemblies shows that the preorganization
Luis C. Pantaleone +8 more
wiley +2 more sources
Research on Star Sensor Imaging Simulation Under Near-Space Hypersonic Non-Equilibrium Flow Conditions. [PDF]
Liao Z +7 more
europepmc +1 more source
Light and Dark Cycles Control the Structural Evolution of Photoresponsive Supramolecular Systems
Here, we report a photoswitchable synthetic peptide that, under light energy cycles, exhibits supramolecular polymorphism coupled to darkness‐driven structural self‐selection. We demonstrate that light sustains a transient assembled state in the form of helical nanoribbons, hindering the system from undergoing a transition to the disassembled state ...
Alejandro Méndez‐Ardoy +6 more
wiley +1 more source
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson +3 more
wiley +2 more sources
The role of the Helmholtz potential on electrocatalytic activity. [PDF]
Chemin A, Godeffroy L, Amans D, Petit T.
europepmc +1 more source

